Proliferating trichilemmal cyst
Updates to Article Attributes
Proliferating trichilemmal cysts are dermal or subcutaneous tumours with squamoid cytologic features and trichilemmal-type keratinisation usually arising in the scalp.
Terminology
A variety of names have been used for this pathology, including proliferating epidermoid cyst, pilar tumour of the scalp, proliferating trichilemmal cyst, proliferating epidermoid cyst, giant hair matrix tumour, hydatidiform keratinous cyst, trichochlamydocarcinoma, and invasive hair matrix tumour 1.
Epidemiology
Proliferating trichilemmal cysts have female predominance 3,4.
Clinical presentation
Proliferating trichilemmal cysts present as lobulated masses within the scalp. They vary considerably in size from a few millimetres to large masses many centimetres in diameter. Occasionally clinical presentation will be with superimposed infection or malignant transformation, although both of these complications are uncommon 3.
Pathology
Although they are mostly benign although, they have local invasive and malignant types 2. They show extensive epithelial proliferation, variable cytologic atypia and mitotic activity.
Radiographic features
CT
Proliferating trichilemmal cysts usually are located within the scalp and appear as multiple complex subcutaneous solid or cystic masses. The cystic components contain high-density proteinaceous material which sometimes layers dependently 3. RinglikeRing-like patterns of mineralisation are also encountered 3.
History and etymology
Proliferating trichilemmal cysts were first defined by Edward Wilson Jones, an English dermatopathologist, in 1966 2.
-<p><strong>Proliferating trichilemmal cysts</strong> are dermal or subcutaneous tumours with squamoid cytologic features and trichilemmal-type keratinisation usually arising in the scalp.</p><h4>Terminology</h4><p>A variety of names have been used for this pathology, including proliferating epidermoid cyst, pilar tumour of the scalp, proliferating trichilemmal cyst, proliferating epidermoid cyst, giant hair matrix tumour, hydatidiform keratinous cyst, trichochlamydocarcinoma, and invasive hair matrix tumour <sup>1</sup>.</p><h4>Epidemiology</h4><p>Proliferating trichilemmal cysts have female predominance <sup>3,4</sup>.</p><h4>Clinical presentation</h4><p>Proliferating trichilemmal cysts present as lobulated masses within the scalp. They vary considerably in size from a few millimetres to large masses many centimetres in diameter. Occasionally clinical presentation will be with superimposed infection or malignant transformation, although both of these complications are uncommon <sup>3</sup>. </p><h4>Pathology</h4><p>Although they are mostly benign although they have local invasive and malignant types <sup>2</sup>. They show extensive epithelial proliferation, variable cytologic atypia and mitotic activity.</p><h4>Radiographic features</h4><h5>CT</h5><p>Proliferating trichilemmal cysts usually are located within the scalp and appear as multiple complex subcutaneous solid or cystic masses. The cystic components contain high-density proteinaceous material which sometimes layers dependently <sup>3</sup>. Ringlike patterns of mineralisation are also encountered <sup>3</sup>. </p><h4>History and etymology</h4><p>Proliferating trichilemmal cysts were first defined by <strong>Edward Wilson Jones</strong>, an English dermatopathologist, in 1966 <sup>2</sup>. </p>- +<p><strong>Proliferating trichilemmal cysts</strong> are dermal or subcutaneous tumours with squamoid cytologic features and trichilemmal-type keratinisation usually arising in the scalp.</p><h4>Terminology</h4><p>A variety of names have been used for this pathology, including proliferating epidermoid cyst, pilar tumour of the scalp, proliferating trichilemmal cyst, proliferating epidermoid cyst, giant hair matrix tumour, hydatidiform keratinous cyst, trichochlamydocarcinoma, and invasive hair matrix tumour <sup>1</sup>.</p><h4>Epidemiology</h4><p>Proliferating trichilemmal cysts have female predominance <sup>3,4</sup>.</p><h4>Clinical presentation</h4><p>Proliferating trichilemmal cysts present as lobulated masses within the scalp. They vary considerably in size from a few millimetres to large masses many centimetres in diameter. Occasionally clinical presentation will be with superimposed infection or malignant transformation, although both of these complications are uncommon <sup>3</sup>. </p><h4>Pathology</h4><p>Although they are mostly benign, they have local invasive and malignant types <sup>2</sup>. They show extensive epithelial proliferation, variable cytologic atypia and mitotic activity.</p><h4>Radiographic features</h4><h5>CT</h5><p>Proliferating trichilemmal cysts usually are located within the scalp and appear as multiple complex subcutaneous solid or cystic masses. The cystic components contain high-density proteinaceous material which sometimes layers dependently <sup>3</sup>. Ring-like patterns of mineralisation are also encountered <sup>3</sup>. </p><h4>History and etymology</h4><p>Proliferating trichilemmal cysts were first defined by <strong>Edward Wilson Jones</strong>, an English dermatopathologist, in 1966 <sup>2</sup>. </p>
Unable to process the form. Check for errors and try again.