Pulmonary leukemic infiltration
Updates to Article Attributes
Pulmonary leukaemic infiltration is a complication that can occur ifin forms of laukaemialeukaemia.
Epidemiology
They can be found in the lungs in around 24-64% of patients with leukaemia on autopsy.
Pathology
Pathologically there is atypical lymphocyte infiltration along the interstitium and the alveolar spaces.
Radiographic features
It can have a variety of radiographic radiographic appearances.
Chest radiograph
Most infiltrates do not appear on chest radiographs 1.
HRCT - chest CT
A variety of pattern have been described include pulmonary infiltrates with alveolar, interstitial, mixed and peribronchial/perivascular patterns 3. There is a general tendency for abnormalities to involve the perilymphatic interstitium 1.
Other reported findings include 1,4
- common
- thickening of bronchovascular bundles: ~ 80%4
- prominence of peripheral pulmonary arteries: ~ 80%4
- non-lobular and non-segmental ground-glass opacities: ~90%4
- uncommon
Differential diagnosis
Due to variable patterns, the differential on CT can be broad and can include 1
See also
-<p><strong>Pulmonary leukaemic infiltration </strong>is a complication that can occur if forms of laukaemia.</p><h4>Epidemiology</h4><p>They can be found in the lungs in around 24-64% of patients with leukaemia on autopsy.</p><h4>Pathology</h4><p>Pathologically there is atypical lymphocyte infiltration along the interstitium and the alveolar spaces.</p><h4>Radiographic features</h4><p>It can have a variety of radiographic radiographic appearances.</p><h5>Chest radiograph</h5><p>Most infiltrates do not appear on chest radiographs <sup>1</sup>.</p><h5>HRCT - chest CT</h5><p>A variety of pattern have been described include pulmonary infiltrates with alveolar, interstitial, mixed and peribronchial/perivascular patterns <sup>3</sup>. There is a general tendency for abnormalities to involve the perilymphatic interstitium <sup>1</sup>.</p><p>Other reported findings include 1,4</p><ul>- +<p><strong>Pulmonary leukaemic infiltration </strong>is a complication that can occur in forms of leukaemia.</p><h4>Epidemiology</h4><p>They can be found in the lungs in around 24-64% of patients with leukaemia on autopsy.</p><h4>Pathology</h4><p>Pathologically there is atypical lymphocyte infiltration along the interstitium and the alveolar spaces.</p><h4>Radiographic features</h4><p>It can have a variety of radiographic radiographic appearances.</p><h5>Chest radiograph</h5><p>Most infiltrates do not appear on chest radiographs <sup>1</sup>.</p><h5>HRCT - chest CT</h5><p>A variety of pattern have been described include pulmonary infiltrates with alveolar, interstitial, mixed and peribronchial/perivascular patterns <sup>3</sup>. There is a general tendency for abnormalities to involve the perilymphatic interstitium <sup>1</sup>.</p><p>Other reported findings include 1,4</p><ul>
-<li>non-lobular and non-segmental <a href="/articles/ground-glass_opacity">ground-glass opacities</a>: ~90%<sup>4</sup>- +<li>non-lobular and non-segmental <a href="/articles/ground-glass-opacification">ground-glass opacities</a>: ~90%<sup>4</sup>
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