Pulmonary tumourlet
Updates to Article Attributes
Pulmonary tumourlets refer to a type of neuroendocrine cell proliferation in the lung. They are at the benign end of the spectrum of neuroendocrine cell proliferation.
Epidemiology
There is a recognised female predilection. Tumourlets are generally encountered in patients around 60 to 70 years of age 2.
Clinical presentation
Most patients tend to be asymptomatic at diagnosis.
Pathology
They are thought to represent tiny peripheral pulmonary carcinoids that differ mainly in size from the larger lesions identified as carcinoid tumours with which they share histological, ultra-structural, and immunohistochemical features . Due to this, they are also called pulmonary carcinoid tumourets by some authors 4. Tumourlets are usually defined as lesions smaller than 5 mm in diameter. They are often multiple.
Tumourlets also lack mitotic activity and do not show necrosis 5.
Associations
They often occur in association with airway damage, emphysema and fibrosis
Radiographic features
CT - HRCT chest
Pulmonary tumourlets may be seen as small pulmonary nodules on CT.
See also
-<p><strong>Pulmonary tumourlets</strong> refer to a type of neuroendocrine cell proliferation in the lung. They are at the benign end of the spectrum of neuroendocrine cell proliferation.</p><h4>Epidemiology</h4><p>There is a recognised female predilection. Tumourlets are generally encountered in patients around 60 to 70 years of age <sup>2</sup>.</p><h4>Clinical presentation</h4><p>Most patients tend to be asymptomatic at diagnosis.</p><h4>Pathology</h4><p>They are thought to represent tiny <a href="/articles/peripheral-pulmonary-carcinoid-tumour" title="Peripheral pulmonary carcinoid tumour">peripheral pulmonary carcinoids</a> that differ mainly in size from the larger lesions identified as carcinoid tumours with which they share histological, ultra-structural, and immunohistochemical features . Due to this, they are also called <strong>pulmonary carcinoid tumourets</strong> by some authors <sup>4</sup>. Tumourlets are usually defined as lesions smaller than 5 mm in diameter. They are often multiple.</p><p>Tumourlets also lack mitotic activity and do not show necrosis <sup>5</sup>.</p><h5>Associations</h5><p>They often occur in association with airway damage, emphysema and fibrosis</p><h4>Radiographic features</h4><h5>CT - HRCT chest</h5><p>Pulmonary tumourlets may be seen as small <a href="/articles/pulmonary-nodule-1" title="Pulmonary nodules">pulmonary nodules</a> on CT. </p><h4>See also</h4><ul>-<li><a href="/articles/diffuse-idiopathic-pulmonary-neuroendocrine-cell-hyperplasia" title="Diffuse idiopathic pulmonary neuroendocrine cell hyperplasia (DIPNECH)">diffuse idiopathic pulmonary neuroendocrine cell hyperplasia</a></li>-<li><a href="/articles/neuroendocrine-tumours-of-the-lung" title="neuroendocrine tumours of the lung">neuroendocrine tumours of the lung</a></li>-</ul>- +<p><strong>Pulmonary tumourlets</strong> refer to a type of neuroendocrine cell proliferation in the lung. They are at the benign end of the spectrum of neuroendocrine cell proliferation.</p><h4>Epidemiology</h4><p>There is a recognised female predilection. Tumourlets are generally encountered in patients around 60 to 70 years of age <sup>2</sup>.</p><h4>Clinical presentation</h4><p>Most patients tend to be asymptomatic at diagnosis.</p><h4>Pathology</h4><p>They are thought to represent tiny <a href="/articles/peripheral-pulmonary-carcinoid-tumour">peripheral pulmonary carcinoids</a> that differ mainly in size from the larger lesions identified as carcinoid tumours with which they share histological, ultra-structural, and immunohistochemical features . Due to this, they are also called <strong>pulmonary carcinoid tumourets</strong> by some authors <sup>4</sup>. Tumourlets are usually defined as lesions smaller than 5 mm in diameter. They are often multiple.</p><p>Tumourlets also lack mitotic activity and do not show necrosis <sup>5</sup>.</p><h5>Associations</h5><p>They often occur in association with airway damage, emphysema and fibrosis</p><h4>Radiographic features</h4><h5>CT - HRCT chest</h5><p>Pulmonary tumourlets may be seen as small <a href="/articles/pulmonary-nodule-1">pulmonary nodules</a> on CT. </p>
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