Radiation-induced neuritis
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Radiation-induced neuritis is a complication of radiotherapy that may present with visible changes on MRI. It is likely to be most relevant in the head and neck region. There is only scarce radiology literature on the subject; and radiation-induced optic neuritis is best documented.
Radiographic features
MRI
Radiation-induced neuritis may demonstrate thickening of the affected nerves with and T2 hyperintense signal and enhancement 1.
- T2: hyperintense perineural signal
- T1C+ (Gd): perineural enhancement
Differential diagnosis
The main differential diagnosis is perineural spread of tumour. However, the latter usually demonstrates more nodular enhancement and is usually FDG avid on PET-scan. If accessible, biopsy of the affected site may provide a definitive answer.
-<p><strong>Radiation-induced neuritis</strong> is a complication of radiotherapy that may present with visible changes on MRI. It is likely to be most relevant in the head and neck region. There is only scarce radiology literature on the subject; radiation-induced <a title="Optic neuritis" href="/articles/optic-neuritis">optic neuritis</a> is best documented.</p><h4>Radiographic features</h4><h5>MRI</h5><p>Radiation-induced neuritis may demonstrate thickening of the affected nerves with and T2 hyperintense signal and enhancement <sup>1</sup>.</p><ul>- +<p><strong>Radiation-induced neuritis</strong> is a complication of <a href="/articles/radiation-therapy">radiotherapy</a> that may present with visible changes on MRI. It is likely to be most relevant in the head and neck region. There is only scarce radiology literature on the subject and radiation-induced <a href="/articles/optic-neuritis">optic neuritis</a> is best documented.</p><h4>Radiographic features</h4><h5>MRI</h5><p>Radiation-induced neuritis may demonstrate thickening of the affected nerves with and T2 hyperintense signal and enhancement <sup>1</sup>.</p><ul>
-</ul><h4>Differential diagnosis</h4><p>The main differential diagnosis is <a title="Perineural spread of tumour" href="/articles/perineural-spread-of-tumour">perineural spread of tumour</a>. However, the latter usually demonstrates more nodular enhancement and is usually FDG avid on PET-scan. If accessible, biopsy of the affected site may provide a definitive answer.</p>- +</ul><h4>Differential diagnosis</h4><p>The main differential diagnosis is <a href="/articles/perineural-spread-of-tumour">perineural spread of tumour</a>. However, the latter usually demonstrates more nodular enhancement and is usually FDG avid on PET-scan. If accessible, biopsy of the affected site may provide a definitive answer.</p>
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