Radiopharmaceuticals
Updates to Article Attributes
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was changed:
Radiopharmaceuticals are drugs that are bound to radioactive substances. The pharmaceutically active portion determines the activity that will be measured and the radioactive portion emits radiation that can be measured by the scanner.
A number of radiopharmaceuticals are radiopharmaceuticals are used in human imaging. They share the physical characteristic of emitting radiation of various kinds. In some cases the emitted particles are detected either directly or indirectly by specialised equipment specialised equipment (e.g. SPECT, PET, gamma camera etc..) to generate imaging. In other cases, the agent is used to have a tissue effect locally.
Properties of an ideal radiopharmaceutical:
- short physical half life time
- eliminated from the body with an effective half life time approximately equaling the examination time to prevent subsequent exposure to the body
- pure gamma emitter by isometric transition
-
gamma rays emitted should be
mono-energetic (approx. 150KeVmonoenergetic (~150KeV) - high specific activity
-
localizelocalise largely and quickly at the target site - decay into a more stable daughter nucleus
- easily and effectively attached to the chemical compound at room temperature
- cheap per patient dose
- can be easily produced or
foundkept at the hospital site
-<p><strong>Radiopharmaceuticals</strong> are drugs that are bound to radioactive substances. The pharmaceutically active portion determines the activity that will be measured and the radioactive portion emits radiation that can be measured by the scanner.</p><p>A number of radiopharmaceuticals are used in human imaging. They share the physical characteristic of emitting radiation of various kinds. In some cases the emitted particles are detected either directly or indirectly by specialised equipment (e.g. SPECT, PET, gamma camera etc..) to generate imaging. In other cases, the agent is used to have a tissue effect locally. </p><p>Properties of an ideal radiopharmaceutical:</p><ul>-<li>short<a href="/articles/half-life-time" title="Half life time"> physical half life time</a>-</li>-<li>eliminated from the body with an <a href="/articles/half-life-time" title="Half life time">effective half life time</a> approximately equaling the examination time to prevent subsequent exposure to the body</li>-<li>pure <a href="/articles/gamma-emitter" title="gamma emitter">gamma emitter</a> by <a href="/articles/isometric-transition" title="isometric transition">isometric transition</a>-</li>- +<p><strong>Radiopharmaceuticals</strong> are drugs that are bound to radioactive substances. The pharmaceutically active portion determines the activity that will be measured and the radioactive portion emits radiation that can be measured by the scanner.</p><p>A number of radiopharmaceuticals are used in human imaging. They share the physical characteristic of emitting radiation of various kinds. In some cases the emitted particles are detected either directly or indirectly by specialised equipment (e.g. SPECT, PET, gamma camera etc) to generate imaging. In other cases, the agent is used to have a tissue effect locally. </p><p>Properties of an ideal radiopharmaceutical:</p><ul>
- +<li>short <a href="/articles/half-life-time">physical half life time</a>
- +</li>
- +<li>eliminated from the body with an <a href="/articles/half-life-time">effective half life time</a> approximately equaling the examination time to prevent subsequent exposure to the body</li>
- +<li>pure <a href="/articles/gamma-emitter">gamma emitter</a> by <a href="/articles/isometric-transition">isometric transition</a>
- +</li>
-<a href="/articles/gamma-rays" title="gamma rays">gamma rays</a> emitted should be mono-energetic (approx. 150KeV)</li>-<li>high <a href="/articles/specific-activity" title="specific activity">specific activity</a>-</li>-<li>localize largely and quickly at the target site</li>-<li>decay into a more stable daughter nucleus</li>-<li>easily and effectively attached to the chemical compound at room temperature</li>-<li>cheap per patient dose</li>-<li>can be easily produced or found at the hospital site</li>- +<a href="/articles/gamma-rays">gamma rays</a> emitted should be monoenergetic (~150KeV)</li>
- +<li>high <a href="/articles/specific-activity">specific activity</a>
- +</li>
- +<li>localise largely and quickly at the target site</li>
- +<li>decay into a more stable daughter nucleus</li>
- +<li>easily and effectively attached to the chemical compound at room temperature</li>
- +<li>cheap per patient dose</li>
- +<li>can be easily produced or kept at the hospital site</li>
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