Reactive airways dysfunction syndrome (RADS) is an airway inflammatory condition often defined as the sudden onset of asthma-like symptoms following high-level exposure to an agent such as corrosive gas, vapor, or fumes. Some publications suggest this a subset or variant of asthma 2-3.
Patients usually have normal premorbid pulmonary physiology and absence of pre-existing bronchial hyperreactivity.
Pathology
Often shows non-specific inflammation, with a cellular infiltrate which is primarily lymphocytic with epithelial desquamation.
History and etymology
The term RADS was originally described by Brooks and Lockers in 1981 as non-immunological form of asthma resulting from exposure to an irritant gas.
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