Citation, DOI, disclosures and article data
Citation:
Iqbal S, Bell D, Scleredema of Buschke. Reference article, Radiopaedia.org (Accessed on 04 May 2024) https://doi.org/10.53347/rID-87782
Scleredema of Buschke, also known as scleredema diabeticorum, is a dermal complication of diabetes mellitus, streptococcus infections and monoclonal gammopathies 1-3.
Risk factors
Risk factors for scleredema of Buschke are 3-6:
- prolonged duration of diabetes mellitus
- obesity
- chronic insulin dependence
The cardinal soft tissue changes are hardening and thickening of the dermis in the region of the shoulder, back and region of the neck.
Breathing difficulties and shoulder movement impairment may occur due to limitations imposed by these soft tissue changes.
Scleredema of Buschke is characterized by non-pitting swelling and thickening of skin secondary to the deposition of collagen and amino glycans in the dermis 2,3,5.
Treatment and prognosis
Phototherapy, physiotherapy, corticosteroids, antibiotics, intravenous immunoglobulin and tight glycemic control are the main treatment options. Partial remission of the disease is documented in most of the cases 6.
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1. Meguerditchian C, Meguerditchian JP, Meguerditchian BlS, Meguerditchian BT, Meguerditchian VrR, Meguerditchian CF, Meguerditchian VB, Meguerditchian. Scleredema adultorum of Buschke: an under recognized skin complication of diabetes. (2006) Diabetes & metabolism. doi:10.1016/s1262-3636(07)70307-5 - Pubmed
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2. Dinato S, Dinato CG, Dinato M, Dinato SA, Dinato RN, Dinato. [Scleredema of Buschke associated with diabetes mellitus type 2: case report and review of the literature]. (2010) Arquivos brasileiros de endocrinologia e metabologia. doi:10.1590/s0004-27302010000900012 - Pubmed
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3. Pitarch G, Torrijos A, Martínez-Aparicio A, Vilata JJ, Fortea JM. Escleredema de Buschke asociado a diabetes mellitus. Estudio de cuatro casos [Scleredema of Buschke associated with diabetes mellitus. Study of four cases]. Actas Dermosifiliogr. 2005 Jan-Feb;96(1):46-9. Spanish. doi: 10.1016/s0001-7310(05)73033-7. PMID: 16476333.
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4. Mohamed M, Mohamed BH, Mohamed BcA, Mohamed MA, Mohamed ZJ, Mohamed. Scleredema adultorum of Buschke with prominent periorbital edema in a Tunisian patient with diabetes mellitus: a case report. (2016) International journal of dermatology. doi:10.1111/ijd.13128 - Pubmed
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5. Ulmer A, Ulmer SLG, Ulmer BJ, Ulmer KtI, Ulmer FG, Ulmer. [Scleredema adultorum Buschke. Case report and review of the literature]. (1998) Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete. doi:10.1007/s001050050700 - Pubmed
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6. Asma Raboudi, Noureddine Litaiem. Scleredema. (2020) Pubmed
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