Splenic lesions and anomalies

Changed by Daniel J Bell, 30 Apr 2021

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There are a number of splenic lesions and anomalies:

Congenital anomalies

Mass lesions

Benign mass lesions

splenic cyst (mnemonic)
splenic pseudocyst
splenic haemangioma: commonest benign splenic lesion
splenic lymphangioma
splenic hamartoma
sclerosing angiomatoid nodular transformation (SANT): fibrosing variant of hamartoma
extramedullary haematopoiesis in the spleen
splenic abscess: sonographically characterised by multiple “target” lesions
splenic hydatid cysts
splenic inflammatory pseudotumour⁷
splenic lipoma
splenic angiomyolipoma
splenic fibroma ⁷
sarcoidosis
focal splenic lesions in type I Gaucher disease ⁸
splenic haematoma ¹⁰

Indeterminate mass lesions

Malignant mass lesions

splenic lymphoma: commonest malignant tumour with splenic involvement ²
angiosarcoma of spleen: commonest primary malignant splenic tumour³
haemagiopericytoma of spleen
splenic metastases: 50% of which are from malignant melanoma
splenic malignant fibrous histocytoma ⁹

Diffuse infiltrative processes

These usually manifest as splenomegaly. Some can present as distinct lesions (e.g. granulomas).

Multifocal splenic lesions

Other abnormalities

splenic rupture
- traumatic: spleen is the most frequently injured intra-abdominal organ in blunt trauma ²
- non-traumatic
splenic infarction
splenosis
splenic peliosis

~~-<li><a href="/articles/splenic-siderotic-nodules">gamna-gandy bodies</a></li>~~
+<li><a title="Splenic siderotic nodules" href="/articles/splenic-siderotic-nodules">splenic siderosis (Gamna-Gandy bodies)</a></li>

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