Superscan

Changed by Mohamed Tofeig, 1 Oct 2021

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A superscan is intense ~~symmetric~~ activity in the bones ~~with~~causing diminished renal and soft tissue activity on a Tc-99m diphosphonate bone scan.

Pathology

Aetiology

This appearance can result from a range of causes:

diffuse metastatic disease
- prostatic carcinoma
- breast cancer
- transitional cell carcinoma (TCC)
- multiple myeloma (some difference in opinion)
- lymphoma
  - patchy uptake nonetheless: look at skull and ribs
  - tends to somewhat spare the distal skeleton
metabolic bone diseases
- renal osteodystrophy
- hyperparathyroidism ¹ (often secondary hyperparathyroidism)
- osteomalacia
  - will involve distal skeleton
  - smoother uptake
myelofibrosis/myelosclerosis
mastocytosis
wide spread Paget disease

Radiographic appearance

A metastatic superscan tends to have uptake throughout the axial skeleton and proximal appendicular skeleton, often somewhat heterogeneous. In contrast, a metabolic superscan tends to be more uniform and involve both the axial and more peripheral skeleton, including the distal extremities, calvarium, and mandible.

-<p>A<strong> superscan </strong>is intense symmetric activity in the bones with diminished renal and soft tissue activity on a Tc-99m diphosphonate <a href="/articles/bone-scintigraphy-1">bone scan</a>.</p><h4>Pathology</h4><h5>Aetiology</h5><p>This appearance can result from a range of causes:</p><ul>
+<p>A<strong> superscan </strong>is intense activity in the bones causing diminished renal and soft tissue activity on a Tc-99m diphosphonate <a href="/articles/bone-scintigraphy-1">bone scan</a>.</p><h4>Pathology</h4><h5>Aetiology</h5><p>This appearance can result from a range of causes:</p><ul>

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