Tc-99m MAG3
Updates to Article Attributes
Body
was changed:
Tc-99m MAG3 (mercaptoacetyltriglycine) is one of the technetium radiopharmaceuticals used in renal imaging.
Characteristics
- photon energy: 140 KeV
- physical half life: 6 hours
- biological half life: 4 hours
- normal distribution: kidneys (100%)
- pharmacokinetics:
- uptake by tubular secretion (97%)
- first pass filtration 60%
- excretion: renal via both glomeruli infiltration and tubular excretion; hence, in paediatric patients and patients with poor renal function this test is considered superior to DTPA scan
- target organ: bladder
- miscellaneous facts
- good quality images with renal insufficiency
- by giving captopril, MAG3 plasma clearance decreases in hypertensive patients with renal artery stenosis but increases in patients without renal artery stenosis
- Cannot measure GFR as it is cleared almost entirely by tubular secretion
Uses, doses and timings
- renal study
- adult dose: 8 mCi IV
- paediatric dose: 0.10 mCi/kg (minimum: 0.4 mCi) 5
- 60 sec flow study; then q5min for 25 min
- +<li>Cannot measure GFR as it is cleared almost entirely by tubular secretion</li>
References changed:
- 6. Ziessman HA, O'Malley JP, Thrall JH. Nuclear medicine. Saunders. ISBN:0323082998 p170
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