Thrombolysis in cerebral infarction (TICI) scale
Updates to Article Attributes
The thrombolysis in cerebral infarction(TICI) grading system was described in 2003 by Higashida et al.1 as a tool for determining the response of thrombolytic therapy for ischaemic stroke. In neurointerventional radiology it is commonly used for patients post endovascular revascularisation. Like Like most therapy response grading systems, it predicts prognosis.
Classification
The original description 1 was based on the angiographic appearances of the treated occluded vessel and the distal branches:
-
Gradegrade 0: no perfusion
-
Gradegrade 1: penetration with minimal perfusion
-
Gradegrade 2: partial perfusion
-
Gradegrade 2A: only partial filling (less than two-thirds) of the entire vascular territory is
visualizedvisualised -
Gradegrade 2B: complete filling of all of the expected vascular territory is
visualizedvisualised but the filling is slower than normal
-
-
Gradegrade 3: complete perfusion
In 2013 Fugate et al. reported marked variability in its definitions and application 2.
A Furthermore, a consensus paper from three collaborative groups published in Stroke in 2013 3 recommended recommended a modified scale, and and a change of name from Thrombolysisto modified treatment in Cerebral Infarction to modified Treatment in Cerebral Infarctioncerebral infarction (mTICI), to better reflect the increased use of endovascular therapies.
See also
-<p>The <strong>thrombolysis in cerebral infarction</strong> (<strong>TICI)</strong> grading system was described in 2003 by Higashida et al. <sup>1</sup> as a tool for determining the response of thrombolytic therapy for <a href="/articles/ischaemic-stroke">ischaemic stroke</a>. In neurointerventional radiology it is commonly used for patients post endovascular revascularisation. Like most therapy response grading systems, it predicts prognosis.</p><h4>Classification</h4><p>The original description <sup>1</sup> was based on the angiographic appearances of the treated occluded vessel and the distal branches:</p><ul>-<li>Grade 0: no perfusion</li>-<li>Grade 1: penetration with minimal perfusion</li>-<li>Grade 2: partial perfusion<ul>-<li>Grade 2A: only partial filling (less than two-thirds) of the entire vascular territory is visualized</li>-<li>Grade 2B: complete filling of all of the expected vascular territory is visualized but the filling is slower than normal</li>- +<p>The <strong>thrombolysis in cerebral infarction</strong> (<strong>TICI)</strong> grading system was described in 2003 by Higashida et al. <sup>1</sup> as a tool for determining the response of thrombolytic therapy for <a href="/articles/ischaemic-stroke">ischaemic stroke</a>. In neurointerventional radiology it is commonly used for patients post endovascular revascularisation. Like most therapy response grading systems, it predicts prognosis.</p><h4>Classification</h4><p>The original description <sup>1</sup> was based on the angiographic appearances of the treated occluded vessel and the distal branches:</p><ul>
- +<li><p>grade 0: no perfusion</p></li>
- +<li><p>grade 1: penetration with minimal perfusion</p></li>
- +<li>
- +<p>grade 2: partial perfusion</p>
- +<ul>
- +<li><p>grade 2A: only partial filling (less than two-thirds) of the entire vascular territory is visualised</p></li>
- +<li><p>grade 2B: complete filling of all of the expected vascular territory is visualised but the filling is slower than normal</p></li>
-<li>Grade 3: complete perfusion</li>-</ul><p>In 2013 Fugate et al. reported marked variability in its definitions and application <sup>2</sup>.</p><p>A consensus paper from three collaborative groups published in Stroke in 2013 <sup>3</sup> recommended a modified scale, and a change of name from Thrombolysis in Cerebral Infarction to <a href="/articles/modified-treatment-in-cerebral-ischaemia-mtici-score">modified Treatment in Cerebral Infarction (mTICI)</a>, to better reflect the increased use of endovascular therapies. </p>- +<li><p>grade 3: complete perfusion</p></li>
- +</ul><p>In 2013 Fugate et al. reported marked variability in its definitions and application <sup>2</sup>. Furthermore, a consensus paper from three collaborative groups published in Stroke in 2013 <sup>3</sup> recommended a modified scale, and a change of name to <a href="/articles/modified-treatment-in-cerebral-infarction-mtici-score">modified treatment in cerebral infarction (mTICI)</a>, to better reflect the increased use of endovascular therapies.</p><h4>See also</h4><ul>
- +<li><p><a href="/articles/modified-treatment-in-cerebral-infarction-mtici-score">modified treatment in cerebral infarction (mTICI) score</a></p></li>
- +<li><p><a href="/articles/expanded-treatment-in-cerebral-infarction-etici-score" title="Expanded treatment in cerebral ischemia (eTICI) score">expanded treatment in cerebral infarction (eTICI) score</a></p></li>
- +</ul>
Sections changed:
- Interventional Radiology
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