Visceral pleural invasion
Updates to Synonym Attributes
Updates to Article Attributes
Body
was changed:
Visceral pleural invasion (VPI) is a feature that can been seen lung cancers. It is defined as tumour extension beyond the elastic layer of viscera pleura. It is considered an aggressive sign one of the most important adverse prognostic factors in in non-small cell lung cancers1.
Grading
There are three described levels of invasion
- PL0: represents tumour invading either the sub-pleural lung parenchyma or superficially the pleural connective tissue beneath the elastic layer
- PL1: refers to a tumour that invades beyond the elastic layer without being exposed on the pleural surface.
- PL2: refers to a tumour that is exposed on the pleural surface, but it does not involve adjacent anatomic structures.
Prognosis
According to one study there was approximately 10-30% worse 5-year survival in tumours with VPI compared to those without VPI.
-</ul><h4>Prognosis</h4><p>According to one study there was approximately 10-30% worse 5-year survival in tumours with VPI compared to those without VPI.</p><p> </p><p> </p>- +</ul><h4>Prognosis</h4><p>According to one study there was approximately 10-30% worse 5-year survival in tumours with VPI compared to those without VPI.</p>
References changed:
- 4. Manac'h D, Riquet M, Medioni J, Le Pimpec-Barthes F, Dujon A, Danel C. Visceral pleura invasion by non-small cell lung cancer: an underrated bad prognostic factor. The Annals of thoracic surgery. 71 (4): 1088-93. <a href="https://www.ncbi.nlm.nih.gov/pubmed/11308141">Pubmed</a> <span class="ref_v4"></span>
- 1. Zhao LL, Xie HK, Zhang LP, Zha JY, Zhou FY, Jiang GN, Chen C. Visceral pleural invasion in lung adenocarcinoma ≤3 cm with ground-glass opacity: a clinical, pathological and radiological study. Journal of thoracic disease. 8 (7): 1788-97. <a href="https://doi.org/10.21037/jtd.2016.05.90">doi:10.21037/jtd.2016.05.90</a> - <a href="https://www.ncbi.nlm.nih.gov/pubmed/27499970">Pubmed</a> <span class="ref_v4"></span>
- 2. Hattori A, Suzuki K, Matsunaga T, Takamochi K, Oh S. Visceral pleural invasion is not a significant prognostic factor in patients with a part-solid lung cancer. The Annals of thoracic surgery. 98 (2): 433-8. <a href="https://doi.org/10.1016/j.athoracsur.2014.04.084">doi:10.1016/j.athoracsur.2014.04.084</a> - <a href="https://www.ncbi.nlm.nih.gov/pubmed/24961845">Pubmed</a> <span class="ref_v4"></span>
- 3. Huang H, Wang T, Hu B, Pan C. Visceral pleural invasion remains a size-independent prognostic factor in stage I non-small cell lung cancer. The Annals of thoracic surgery. 99 (4): 1130-9. <a href="https://doi.org/10.1016/j.athoracsur.2014.11.052">doi:10.1016/j.athoracsur.2014.11.052</a> - <a href="https://www.ncbi.nlm.nih.gov/pubmed/25704861">Pubmed</a> <span class="ref_v4"></span>
- 5. Kang JH, Kim KD, Chung KY. Prognostic value of visceral pleura invasion in non-small cell lung cancer. European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery. 23 (6): 865-9. <a href="https://www.ncbi.nlm.nih.gov/pubmed/12829059">Pubmed</a> <span class="ref_v4"></span>
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