Citation, DOI, disclosures and article data
Citation:
Gaillard F, Sharma R, Campos A, Wilbrand knee (optic radiation). Reference article, Radiopaedia.org (Accessed on 18 May 2024) https://doi.org/10.53347/rID-100092
Disclosures:
At the time the article was created Frank Gaillard had the following disclosures:
- Radiopaedia Australia Pty Ltd, Founder and CEO (ongoing)
- Biogen Australia Pty Ltd, Investigator-Initiated Research Grant for CAD software development in multiple sclerosis (past)
These were assessed during peer review and were determined to
not be relevant to the changes that were made.
View Frank Gaillard's current disclosures
The Wilbrand knee refers to a small anterior loop of axons from the medial retina passing a short distance into the contralateral prechiasmatic optic nerve after decussating in the optic chiasm. It is said to account for the occurrence of the junctional scotoma caused by lesions at the junction of the optic nerve and chiasm; characterized by ipsilateral central scotoma with additional superior temporal visual field defect in the contralateral eye.
The existence of the Wilbrand knee is, however, controversial and some research suggests that it is an artifact resulting from long-term enucleation 1,3.
History and etymology
Hermann Wilbrand (1851-1935), was a German ophthalmologist 5 and published a description of these fibers in 1904 4.
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1. Horton J. Wilbrand's Knee of the Primate Optic Chiasm is an Artefact of Monocular Enucleation. Trans Am Ophthalmol Soc. 1997;95:579-609. PMC1298376 - Pubmed
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2. Horton J. Wilbrand's Knee: To Be or Not to Be a Knee? J Neuroophthalmol. 2020;40 Suppl 1(Suppl 1):S7-S14. doi:10.1097/WNO.0000000000000988 - Pubmed
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3. Grzybowski A & Kanclerz P. The Wilbrand's Knee Does Not Exist in the Optic Chiasm. Childs Nerv Syst. 2018;34(11):2133. doi:10.1007/s00381-018-3969-5 - Pubmed
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4. Wilbrand H, Saenger A. Die Neurologie des Auges. Vol. 3, part 1. Wiesbaden, Germany: J. Bergmann, 1904:98–120.
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5. Jan Dirk Blom. A Dictionary of Hallucinations. (2009) ISBN: 9781441912237 - Google Books
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