Lithium induced renal disease

Case contributed by Tom Foster
Diagnosis almost certain

Presentation

Newly deranged LFTs, no obvious cause on US. Surgical team requested MRCP. Background of chronic renal impairment, longstanding lithium treatment for bipolar disorder.

Patient Data

Age: 45 years
Gender: Female
mri

Unremarkable appearance of the gallbladder, with 3 mm polyp but no obvious calculi.

Case Discussion

Lithium is recognized to cause direct damage to the renal tubules. Patients with lithium-induced renal disease will show a steady decline in renal function. The kidneys often demonstrate numerous microcysts.

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