Adrenal hemangioma
Updates to Case Attributes
The left adrenal gland demonstrates a soft tissue mass (27HUpatient therefore went on non-contrast phase) which demonstrates prominent arterial enhancement peripherally and gradually fills in. It remains a similar attenuation to the aorta on all sequences including delayed scanshave resection.
Incidental note is made of a simple (grade 1) renal cyst on the left. Histology
The features, although consistent with the eventual diagnosis of an adrenal haemangioma, are indeterminate and a malignant lesion (e.g. adrenal metastasis or adrenal carcinoma) cannot be excluded.
Histology
Macroscopic description
This is an adrenal gland weighing 29 grams, covered covered in fatty tissue tissue measuring 75 75 x 40 x 25mm. On On one aspect of the the adrenal gland gland, the the covering fat fat is sufficient sufficient. This This surface is inked blue, while the other surface is inked black. The The adrenal gland is serially sliced sliced to reveal reveal within the the gland parenchyma parenchyma there is reddish black tumour mass, measuring measuring 18 x 14 x 24mm 24mm in maximum dimension. Most of the tumour mass tumour mass is surrounded by surrounded by a rim of adrenal parenchyma adrenal parenchyma. Focally the tumour is is present on the surface surface of the adrenal adrenal gland (inked black) with no overlying fat or adrenal gland. The The remaining adrenal gland is unremarkable unremarkable.
Microscopic description description
Sections of adrenal gland show a circumscribed circumscribed but non-encapsulated tumour within adrenal gland, involving cortex and and medulla. There There are irregularly shaped anastomosing vascular channels present anastomosing vascular channels present, separated by variably variably abundant hyalinised collagenous stroma. The vessels are lined vessels are lined by endothelial cells with small cells with small nuclei with only with only mild pleomorphism pleomorphism, and and mitotic figures are are not identified identified. In areas In areas, there are larger larger vessels containing organizing blood organizing blood and fibrin fibrin clot. The features are are most in keeping with a haemangioma. Focally Focally, the the lesion is disrupted; however, in intact regions, the lesion is clear of margins. The The adjacent adrenal gland is unremarkable. There There is no evidence of metastatic carcinoma.
Final
Final diagnosis
Left adrenalectomy - Adrenal haemangioma. No metastatic carcinoma identified.
-<p>The left adrenal gland demonstrates a soft tissue mass (27HU on non-contrast phase) which demonstrates prominent arterial enhancement peripherally and gradually fills in. It remains a similar attenuation to the aorta on all sequences including delayed scans. </p><p>Incidental note is made of a simple (grade 1) renal cyst on the left. </p><p>The features, although consistent with the eventual diagnosis of an <a href="/articles/adrenal-haemangioma" title="adrenal haemangioma">adrenal haemangioma</a>, are indeterminate and a malignant lesion (e.g. <a href="/articles/adrenal-metastasis" title="adrenal metastasis">adrenal metastasis</a> or <a href="/articles/adrenal-cortical-carcinoma-1" title="Adrenal carcinoma">adrenal carcinoma</a>) cannot be excluded. </p><h4>Histology</h4><h5>Macroscopic description</h5><p>This is an adrenal gland weighing 29 grams,  covered in fatty  tissue measuring  75 x 40 x 25mm.  On one aspect of  the adrenal  gland,  the covering  fat is  sufficient.  This surface is inked blue, while the other surface is inked black.  The adrenal gland is serially  sliced to  reveal within  the gland  parenchyma there is reddish black tumour mass,  measuring 18 x 14 x  24mm in maximum dimension. Most of the  tumour  mass is  surrounded  by a rim of  adrenal  parenchyma. Focally the tumour  is present on the  surface of the  adrenal gland (inked black) with no overlying fat or adrenal gland.  The remaining adrenal gland is  unremarkable.   </p><h5>Microscopic description</h5><p>Sections of adrenal gland show a  circumscribed but non-encapsulated tumour within adrenal gland, involving cortex  and medulla.  There are irregularly shaped  anastomosing  vascular  channels  present,   separated by  variably abundant   hyalinised   collagenous   stroma.   The  vessels  are  lined by endothelial  cells  with  small nuclei  with  only mild  pleomorphism,  and mitotic figures  are not  identified.  In  areas, there are  larger vessels containing  organizing  blood and  fibrin clot.   The features  are most in keeping with a haemangioma.  Focally,  the lesion is disrupted; however, in intact regions, the lesion is clear of margins.  The adjacent adrenal gland is unremarkable.  There is no evidence of metastatic carcinoma.</p><h5> Final diagnosis</h5><p>Left adrenalectomy  - <a href="/articles/adrenal-haemangioma" title="Adrenal haemangioma">Adrenal haemangioma</a>. No metastatic carcinoma identified.</p>- +<p>The patient therefore went on to have resection. </p><p><strong>Histology</strong></p><p>Macroscopic description</p><p>This is an adrenal gland weighing 29 grams, covered in fatty tissue measuring 75 x 40 x 25mm. On one aspect of the adrenal gland, the covering fat is sufficient. This surface is inked blue, while the other surface is inked black. The adrenal gland is serially sliced to reveal within the gland parenchyma there is reddish black tumour mass, measuring 18 x 14 x 24mm in maximum dimension. Most of the tumour mass is surrounded by a rim of adrenal parenchyma. Focally the tumour is present on the surface of the adrenal gland (inked black) with no overlying fat or adrenal gland. The remaining adrenal gland is unremarkable. </p><p>Microscopic description</p><p>Sections of adrenal gland show a circumscribed but non-encapsulated tumour within adrenal gland, involving cortex and medulla. There are irregularly shaped anastomosing vascular channels present, separated by variably abundant hyalinised collagenous stroma. The vessels are lined by endothelial cells with small nuclei with only mild pleomorphism, and mitotic figures are not identified. In areas, there are larger vessels containing organizing blood and fibrin clot. The features are most in keeping with a haemangioma. Focally, the lesion is disrupted; however, in intact regions, the lesion is clear of margins. The adjacent adrenal gland is unremarkable. There is no evidence of metastatic carcinoma.</p><p><strong>Final diagnosis</strong></p><p>Left adrenalectomy - <a href="/articles/adrenal-haemangioma">Adrenal haemangioma</a>. No metastatic carcinoma identified.</p>
Updates to Study Attributes
The left adrenal gland demonstrates a soft tissue mass (27HU on non-contrast phase) which demonstrates prominent arterial enhancement peripherally and gradually fills in. It remains a similar attenuation to the aorta on all sequences including delayed scans.
Incidental note is made of a simple (grade 1) renal cyst on the left.
Conclusion:
The features indeterminate and a malignant lesion (e.g. adrenal metastasis or adrenal carcinoma) cannot be excluded.