Adrenal hemangioma

Case contributed by Frank Gaillard , 11 Oct 2010
Diagnosis certain
Changed by Frank Gaillard, 31 Aug 2015

Updates to Case Attributes

Body was changed:

The left adrenal gland demonstrates a soft tissue mass (27HUpatient therefore went on non-contrast phase) which demonstrates prominent arterial enhancement peripherally and gradually fills in. It remains a similar attenuation to the aorta on all sequences including delayed scanshave resection.

Incidental note is made of a simple (grade 1) renal cyst on the left. Histology

The features, although consistent with the eventual diagnosis of an adrenal haemangioma, are indeterminate and a malignant lesion (e.g. adrenal metastasis or adrenal carcinoma) cannot be excluded. 

Histology

Macroscopic description

This is an adrenal gland weighing 29 grams,  covered covered in fatty  tissue tissue measuring  75 75 x 40 x 25mm.  On On one aspect of  the the adrenal  gland gland,  the the covering  fat fat is  sufficient sufficient.  This This surface is inked blue, while the other surface is inked black.  The The adrenal gland is serially  sliced sliced to  reveal reveal within  the the gland  parenchyma parenchyma there is reddish black tumour mass,  measuring measuring 18 x 14 x  24mm 24mm in maximum dimension. Most of the  tumour  mass tumour  mass is  surrounded  by surrounded  by a rim of  adrenal  parenchyma adrenal  parenchyma. Focally the tumour  is is present on the  surface surface of the  adrenal adrenal gland (inked black) with no overlying fat or adrenal gland.  The The remaining adrenal gland is  unremarkable unremarkable.

Microscopic description description

Sections of adrenal gland show a  circumscribed circumscribed but non-encapsulated tumour within adrenal gland, involving cortex  and and medulla.  There There are irregularly shaped  anastomosing  vascular  channels  present anastomosing  vascular  channels  present, separated by  variably variably abundant hyalinised collagenous stroma. The  vessels  are  lined vessels  are  lined by endothelial  cells  with  small cells  with  small nuclei  with  only with  only mild  pleomorphism pleomorphism,  and and mitotic figures  are are not  identified identified.  In  areas In  areas, there are  larger larger vessels containing  organizing  blood organizing  blood and  fibrin fibrin clot. The features  are are most in keeping with a haemangioma.  Focally Focally,  the the lesion is disrupted; however, in intact regions, the lesion is clear of margins.  The The adjacent adrenal gland is unremarkable.  There There is no evidence of metastatic carcinoma.

 Final

Final diagnosis

Left adrenalectomy - Adrenal haemangioma. No metastatic carcinoma identified.

  • -<p>The left adrenal gland demonstrates a soft tissue mass (27HU on non-contrast phase) which demonstrates prominent arterial enhancement peripherally and gradually fills in. It remains a similar attenuation to the aorta on all sequences including delayed scans.&#160;</p><p>Incidental note is made of a simple (grade 1) renal cyst on the left.&#160;</p><p>The features, although consistent with the eventual diagnosis of an <a href="/articles/adrenal-haemangioma" title="adrenal haemangioma">adrenal haemangioma</a>, are indeterminate and a malignant lesion (e.g. <a href="/articles/adrenal-metastasis" title="adrenal metastasis">adrenal metastasis</a> or <a href="/articles/adrenal-cortical-carcinoma-1" title="Adrenal carcinoma">adrenal carcinoma</a>) cannot be excluded.&#160;</p><h4>Histology</h4><h5>Macroscopic description</h5><p>This is an adrenal gland weighing 29 grams, &#160;covered in fatty &#160;tissue measuring &#160;75 x 40 x 25mm. &#160;On one aspect of &#160;the adrenal &#160;gland, &#160;the covering &#160;fat is &#160;sufficient. &#160;This surface is inked blue, while the other surface is inked black. &#160;The adrenal gland is serially &#160;sliced to &#160;reveal within &#160;the gland &#160;parenchyma there is reddish black tumour mass, &#160;measuring 18 x 14 x &#160;24mm in maximum dimension. Most of the &#160;tumour &#160;mass is &#160;surrounded &#160;by a rim of &#160;adrenal &#160;parenchyma. Focally the tumour &#160;is present on the &#160;surface of the &#160;adrenal gland (inked black) with no overlying fat or adrenal gland. &#160;The remaining adrenal gland is &#160;unremarkable. &#160;&#160;</p><h5>Microscopic&#160;description</h5><p>Sections of adrenal gland show a &#160;circumscribed but non-encapsulated tumour within adrenal gland, involving cortex &#160;and medulla. &#160;There are irregularly shaped &#160;anastomosing &#160;vascular &#160;channels &#160;present, &#160; separated by &#160;variably abundant &#160; hyalinised &#160; collagenous &#160; stroma. &#160; The &#160;vessels &#160;are &#160;lined by endothelial &#160;cells &#160;with &#160;small nuclei &#160;with &#160;only mild &#160;pleomorphism, &#160;and mitotic figures &#160;are not &#160;identified. &#160;In &#160;areas, there are &#160;larger vessels containing &#160;organizing &#160;blood and &#160;fibrin clot. &#160; The features &#160;are most in keeping with a haemangioma. &#160;Focally, &#160;the lesion is disrupted; however, in intact regions, the lesion is clear of margins. &#160;The adjacent adrenal gland is unremarkable. &#160;There is no evidence of metastatic carcinoma.</p><h5>&#160;Final diagnosis</h5><p>Left adrenalectomy &#160;- <a href="/articles/adrenal-haemangioma" title="Adrenal haemangioma">Adrenal haemangioma</a>. No metastatic carcinoma identified.</p>
  • +<p>The patient therefore went on to have resection. </p><p><strong>Histology</strong></p><p>Macroscopic description</p><p>This is an adrenal gland weighing 29 grams,  covered in fatty  tissue measuring  75 x 40 x 25mm.  On one aspect of  the adrenal  gland,  the covering  fat is  sufficient.  This surface is inked blue, while the other surface is inked black.  The adrenal gland is serially  sliced to  reveal within  the gland  parenchyma there is reddish black tumour mass,  measuring 18 x 14 x  24mm in maximum dimension. Most of the  tumour  mass is  surrounded  by a rim of  adrenal  parenchyma. Focally the tumour  is present on the  surface of the  adrenal gland (inked black) with no overlying fat or adrenal gland.  The remaining adrenal gland is  unremarkable.   </p><p>Microscopic description</p><p>Sections of adrenal gland show a  circumscribed but non-encapsulated tumour within adrenal gland, involving cortex  and medulla.  There are irregularly shaped  anastomosing  vascular  channels  present,   separated by  variably abundant   hyalinised   collagenous   stroma.   The  vessels  are  lined by endothelial  cells  with  small nuclei  with  only mild  pleomorphism,  and mitotic figures  are not  identified.  In  areas, there are  larger vessels containing  organizing  blood and  fibrin clot.   The features  are most in keeping with a haemangioma.  Focally,  the lesion is disrupted; however, in intact regions, the lesion is clear of margins.  The adjacent adrenal gland is unremarkable.  There is no evidence of metastatic carcinoma.</p><p><strong>Final diagnosis</strong></p><p>Left adrenalectomy  - <a href="/articles/adrenal-haemangioma">Adrenal haemangioma</a>. No metastatic carcinoma identified.</p>
Diagnostic Certainty was set to .

Updates to Study Attributes

Findings was added:

The left adrenal gland demonstrates a soft tissue mass (27HU on non-contrast phase) which demonstrates prominent arterial enhancement peripherally and gradually fills in. It remains a similar attenuation to the aorta on all sequences including delayed scans. 

Incidental note is made of a simple (grade 1) renal cyst on the left. 

Conclusion:

The features indeterminate and a malignant lesion (e.g. adrenal metastasis or adrenal carcinoma) cannot be excluded. 

Images Changes:

Image CT (non-contrast) ( update )

Perspective was set to Axial.

Image CT (C+ arterial phase) ( update )

Perspective was set to Axial.

Image CT (C+ portal venous phase) ( update )

Perspective was set to Axial.

Image CT (C+ delayed) ( update )

Perspective was set to Axial.

Image CT (ROIs HU) ( update )

Perspective was set to Axial.
Specifics changed from to ROIs HU.

How to use cases

You can use Radiopaedia cases in a variety of ways to help you learn and teach.

Creating your own cases is easy.

Updating… Please wait.

 Unable to process the form. Check for errors and try again.

 Thank you for updating your details.