Air crescent sign

Case contributed by Frank Gaillard , 22 Feb 2010
Diagnosis probable
Changed by Frank Gaillard, 31 Aug 2015

Updates to Case Attributes

Age was set to 14 years.
Body was changed:

Sagittal reformat from a CT scan of the chest, performed on a 14 year-old female with acute myeloblastic leukaemia.

The image shows a rounded cavity in the apical right upper lobe, with a non-dependant soft-tissue nodule within it. There is some subtle ground-glass opacity surrounding the lesion. There were several other similar lesions in the right lung (not shown).

The imaging features, combined with the clinical history, are characteristic of invasive fungal infection, most commonly due to Aspergillus spp..Care should be taken to avoid confusion with mycetoma, which occurs inpatients with pre-existing lung cavities, is gravity-dependant, andlacks the ground-glass halo.

Invasive aspergillosis occurs inimmunosuppressed individuals and carries a 65-90% mortality rate ifimproperly treated. Cavitation occurs in the recovery phase, and thustends to indicate a better prognosis.

Reference: Abramson S. The Air-Crescent Sign. Radiology. 2001; 218:230-232

  • -<p>Sagittal reformat from a CT scan of the chest, performed on a 14 year-old female with acute myeloblastic leukaemia.</p> <p>The
  • -image shows a rounded cavity in the apical right upper lobe, with a
  • -non-dependant soft-tissue nodule within it. There is some subtle
  • -ground-glass opacity surrounding the lesion. There were several other
  • -similar lesions in the right lung (not shown).</p> <p>The imaging features, combined with the clinical history, are characteristic of invasive fungal infection, most commonly due to <em>Aspergillus </em>spp..
  • -Care should be taken to avoid confusion with <a href="/articles/mycetoma" title="mycetoma">mycetoma</a>, which occurs in
  • -patients with&#160; pre-existing lung cavities, is gravity-dependant, and
  • -lacks the ground-glass halo.</p><p><a href="/articles/invasive-aspergillosis" title="Invasive aspergillosis">Invasive aspergillosis</a> occurs in
  • -immunosuppressed individuals and carries a 65-90% mortality rate if
  • -improperly treated. Cavitation occurs in the recovery phase, and thus
  • -tends to indicate a better prognosis. </p><p><strong>Reference</strong>: Abramson S. The Air-Crescent Sign. <em>Radiology</em>. 2001; 218:230-232</p>
  • +<p>The imaging features, combined with the clinical history, are characteristic of invasive fungal infection, most commonly due to <em>Aspergillus </em>spp.. Care should be taken to avoid confusion with <a href="/articles/mycetoma">mycetoma</a>, which occurs in patients with  pre-existing lung cavities, is gravity-dependant, and lacks the ground-glass halo.</p><p><a href="/articles/invasive-aspergillosis">Invasive aspergillosis</a> occurs in immunosuppressed individuals and carries a 65-90% mortality rate if improperly treated. Cavitation occurs in the recovery phase, and thus tends to indicate a better prognosis.</p><p><strong>Reference</strong>: Abramson S. The Air-Crescent Sign. <em>Radiology</em>. 2001; 218:230-232</p>
Diagnostic Certainty was set to .
Suitable For Quiz was set to .

Updates to Study Attributes

Findings was added:

Sagittal reformat from a CT scan of the chest, performed on a 14 year-old female with acute myeloblastic leukaemia.

The image shows a rounded cavity in the apical right upper lobe, with a non-dependant soft-tissue nodule within it. There is some subtle ground-glass opacity surrounding the lesion. There were several other similar lesions in the right lung (not shown).

Images Changes:

Image CT (lung window) ( update )

Description was removed:
Air crescent sign
Single Or Stack Root was set to .
Specifics was set to lung window.
Perspective was set to Sagittal.

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