Cerebral radiation necrosis and radiation induced optic neuropathy
Updates to Case Attributes
MRI features highly suggestive of a cerebral radiation necrosis with a radiation-induced optic neuropathy as well as a fatty replacement of bone marrow.
Radiation-induced optic neuropathy is considered as a common and severe ocular complication following external beam radiation therapy for nasopharyngeal carcinoma. It is theoccurs as a result of a radiation necrosis involving the anterior visual pathway.
-<p>MRI features highly suggestive of a <a href="/articles/cerebral-radiation-necrosis-1">cerebral radiation necrosis</a> with a radiation-induced optic neuropathy as well as a fatty replacement of bone marrow.</p><p>Radiation-induced optic neuropathy is considered as a common and severe ocular complication following external beam radiation therapy for nasopharyngeal carcinoma. It is the result of a radiation necrosis involving the anterior visual pathway.</p>- +<p>MRI features highly suggestive of a <a href="/articles/cerebral-radiation-necrosis-1">cerebral radiation necrosis</a> with a radiation-induced optic neuropathy as well as a fatty replacement of bone marrow.</p><p>Radiation-induced optic neuropathy is considered as a common and severe ocular complication following external beam radiation therapy for nasopharyngeal carcinoma. It occurs as a result of a radiation necrosis involving the anterior visual pathway.</p>
Tags changed:
- radiation injury
- optic nerve
- gliosis versus encephalomalacia
Systems changed:
- Head & Neck
Updates to Link Attributes
Updates to Primarylink Attributes
Updates to Study Attributes
Both temporal lobes, as well as the basal frontal lobes, show an abnormal high signal intensity on FLAIR and T2WI with heterogeneous enhancement involving both graygrey and white matter. The left optic nerve shows an abnormal high signal intensity on T2WI withand enhancement, highly suggestive of radiation-induced optic neuropathy. Signs of bilateral mastoiditis which could be also radio-induced.
No soft tissue mass or abnormal enhancement within the nasopharynx. No cervical lymphadenopathy is seen.
An increased bone marrow signal intensity on T1WI is noted, involving the skull base, as well as the upper cervical vertebrae, maxilla, and mandible, indicating a radiation-induced fatty replacement ofbone marrow.