Cystic adventitial disease

Case contributed by Julieta Rosana Crosta , 2 Mar 2018
Diagnosis certain
Changed by Daniel J Bell, 2 Nov 2021

Updates to Case Attributes

Age changed from 45 to 45 years.
Presentation was changed:
Patient with pain in the leftLeft calf and knee pain for several months, that has been exacerbated after intense walking in the last few days.
Body was changed:

Cystic disease of the adventitia is more frequent in males and predominantly affects the popliteal artery, although it can affect other arteries. The cysts contain a proteinaceous or mucinous fluid, and surround the artery. They can generate extrinsic compression of the arterial lumen, especially during exercise, which is why they produce claudication. At rest, they do not usually give symptoms. Within the possible etiologies, trauma of the artery wall is considered the most probable.

Ultrasound is a very good method for the examination of the painful knee and to rule out other differential diagnoses such as Baker's cyst or venousdeep vein thrombosis. The cysts are observed as periarterial anechoic images, which do not show flow with color or power Doppler.

With Doppler ultrasound, dynamic manoeuvres can be performed and the compression of the lumen can be demonstrated with muscle contraction.

On MRI, the cysts are hyperintense on T2, and are usually hypointense on T1 although this depends on the mucin or protein content.

  • -<p>Cystic disease of the adventitia is more frequent in males and predominantly affects the popliteal artery, although it can affect other arteries. The cysts contain a proteinaceous or mucinous fluid, and surround the artery. They can generate extrinsic compression of the arterial lumen, especially during exercise, which is why they produce claudication. At rest, they do not usually give symptoms. Within the possible etiologies, trauma of the artery wall is considered the most probable. </p><p>Ultrasound is a very good method for the examination of the painful knee and to rule out other differential diagnoses such as Baker's cyst or venous thrombosis. The cysts are observed as periarterial anechoic images, which do not show flow with color or power Doppler.</p><p>With Doppler ultrasound, dynamic manoeuvres can be performed and the compression of the lumen can be demonstrated with muscle contraction.</p><p>On MRI, the cysts are hyperintense on T2, and are usually hypointense on T1 although this depends on the mucin or protein content.</p>
  • +<p><a title="Cystic adventitial disease" href="/articles/cystic-adventitial-disease">Cystic disease of the adventitia</a> is more frequent in males and predominantly affects the <a title="Popliteal artery" href="/articles/popliteal-artery">popliteal artery</a>, although it can affect other arteries. The cysts contain a proteinaceous or mucinous fluid, and surround the artery. They can generate extrinsic compression of the arterial lumen, especially during exercise, which is why they produce <a title="claudication" href="/articles/claudication">claudication</a>. At rest, they do not usually give symptoms. Within the possible etiologies, trauma of the artery wall is considered the most probable.</p><p>Ultrasound is a very good method for the examination of the painful knee and to rule out other differential diagnoses such as <a title="Baker cyst" href="/articles/baker-cyst-2">Baker cyst</a> or <a title="DVT" href="/articles/deep-vein-thrombosis">deep vein thrombosis</a>. The cysts are observed as periarterial anechoic images, which do not show flow with color or power Doppler.</p><p>With Doppler ultrasound, dynamic manoeuvres can be performed and the compression of the lumen can be demonstrated with muscle contraction.</p><p>On MRI, the cysts are hyperintense on T2, and are usually hypointense on T1 although this depends on the mucin or protein content.</p>

References changed:

  • 1. Kawarai S, Fukasawa M, Kawahara Y. Adventitial Cystic Disease of the Popliteal Artery. Ann Vasc Dis. 2012;5(2):190-3. <a href="https://doi.org/10.3400/avd.cr.11.00069">doi:10.3400/avd.cr.11.00069</a> - <a href="https://www.ncbi.nlm.nih.gov/pubmed/23555509">Pubmed</a>
  • 2. Mino M, Garrigues D, Pierce D, Arko F. Cystic Adventitial Disease of the Popliteal Artery. J Vasc Surg. 2009;49(5):1324. <a href="https://doi.org/10.1016/j.jvs.2008.10.060">doi:10.1016/j.jvs.2008.10.060</a> - <a href="https://www.ncbi.nlm.nih.gov/pubmed/19307092">Pubmed</a>
  • 3. Wright L, Matchett W, Cruz C et al. Popliteal Artery Disease: Diagnosis and Treatment. Radiographics. 2004;24(2):467-79. <a href="https://doi.org/10.1148/rg.242035117">doi:10.1148/rg.242035117</a> - <a href="https://www.ncbi.nlm.nih.gov/pubmed/15026594">Pubmed</a>
  • 4. Tsilimparis N, Hanack U, Yousefi S, Alevizakos P, Rückert R. Cystic Adventitial Disease of the Popliteal Artery: An Argument for the Developmental Theory. J Vasc Surg. 2007;45(6):1249-52. <a href="https://doi.org/10.1016/j.jvs.2007.01.051">doi:10.1016/j.jvs.2007.01.051</a> - <a href="https://www.ncbi.nlm.nih.gov/pubmed/17543690">Pubmed</a>
  • 5. Peterson J, Kransdorf M, Bancroft L, Murphey M. Imaging Characteristics of Cystic Adventitial Disease of the Peripheral Arteries: Presentation as Soft-Tissue Masses. AJR Am J Roentgenol. 2003;180(3):621-5. <a href="https://doi.org/10.2214/ajr.180.3.1800621">doi:10.2214/ajr.180.3.1800621</a> - <a href="https://www.ncbi.nlm.nih.gov/pubmed/12591663">Pubmed</a>
  • Shun-ichi Kawarai; Manabu Fukasawa and Yu Kawahara. Adventitial Cystic Disease of the Popliteal Artery. Case report. Ann Vasc Dis Vol.5, No.2; 2012; pp 190–193
  • Mino M. et al. Cystic adventitial disease of the popliteal artery. Journal of Vascular Surgery Volume 49, Issue 5, May 2009, Page 1324
  • Wright L. et al. Popliteal Artery Disease: Diagnosis and Treatment. RadioGraphics 2004; 24:467– 479
  • Tsilimparis et al. Cystic adventitial disease of the popliteal artery: An argument for the developmental theory. Journal of Vascular Surgery. Juan 2007. Volume 45, Number 6. 1249 - 1252
  • Peterson, Jeffrey J.; Kransdorf Mark J., Bancrof Laura W. and Murphey Mark D. Imaging Characteristics of Cystic Adventitial Disease of the Peripheral Arteries: Presentation as Soft-Tissue Masses. AJR 2003;180:621–625

Tags changed:

  • legacy

Updates to Study Attributes

Caption was added:
US popliteal fossa

Updates to Freetext Attributes

Description was added:
  • Note: This case has been tagged as "legacy" as it no longer meets image preparation and/or other case publication guidelines.

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