Hepatic adenomatosis

Case contributed by Jason Murri , 6 Feb 2018
Diagnosis certain
Changed by Jason Murri, 9 Feb 2018

Updates to Freetext Attributes

Description was added:

Pathology Report

FINAL DIAGNOSIS: 

 NODULE, LIVER, ULTRASOUND-GUIDED CORE BIOPSY: 1. LIVER CELL ADENOMA (SEE COMMENT). 2. NO EVIDENCE OF METASTATIC CARCINOMA. 

COMMENT: The morphologic and immunohistochemical findings are most consistent with liver cell adenoma. If multiple, the diagnosis "liver cell adenomatosis" has been used. 

CLINICAL HISTORY:       Multiple liver nodules; long history of oral                         contraceptive use PREOPERATIVE           Same DIAGNOSIS: POSTOPERATIVE          Same DIAGNOSIS: SPECIMEN(S):            Liver mass

GROSS DESCRIPTION: Received in formalin labeled with the patient's name and "liver biopsy" and consists of five red-tan, needle-core fragments ranging from 0.2 x 0.1 x 0.1 cm to the largest of 2.0 cm in length with a diameter of 0.1 cm. The specimen is submitted entirely within two mesh cassettes. Due to the minute size of the smallest fragment, it may not survive processing. 

MICROSCOPIC DESCRIPTION: A microscopic examination has been performed and the findings incorporated into the diagnosis. 

 Immunohistochemical/special stain(s) is/are performed on block(s) A1 and A2. 

 Medical necessity for performing stain(s): To enable diagnosis 

 The stain(s) is/are evaluated following validation of appropriate control reactivity, with the following result(s):  STAIN/RESULT 

 Reticulin Highlights hepatic architecture consistent with adenoma  CD31  Highlights vascularity  CD34  "Complete" staining pattern  Beta catenin Uniform membranous staining 

Updates to Case Attributes

Body was changed:

Prior contrast enhanced CT scan from about 10 years before showed an unremarkable appearance of the liver. Ultrasound guided liver biopsy was performed for the right inferior lobe lesion which was most consistent with a hepatic adenoma, adenomatosis in the setting of multiple massespathology report included above.

  • -<p>Prior contrast enhanced CT scan from about 10 years before showed an unremarkable appearance of the liver. Ultrasound guided liver biopsy was performed for the right inferior lobe lesion which was most consistent with a hepatic adenoma, adenomatosis in the setting of multiple masses.</p>
  • +<p>Prior contrast enhanced CT scan from about 10 years before showed an unremarkable appearance of the liver. Ultrasound guided liver biopsy was performed for the right inferior lobe lesion with pathology report included above.</p>
Diagnostic Certainty was set to .

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