Localized pigmented villonodular synovitis

Case contributed by Domenico Nicoletti
Diagnosis almost certain

Presentation

Knee pain without trauma. Incidental finding.

Patient Data

Age: 50 years
Gender: Female

MRI Left Knee without and with contrast

In the popliteal fossa, laterally, at the posterior surface of the femoral condyle in the gradient echo T2 sequences, is visible oval formation with blooming artifact caused by magnetic susceptibility from intracellular hemosiderin deposits.

Case Discussion

Pigmented villonodular synovitis (PVNS) is a rare, benign, proliferative disease of the synovial membrane of joints, tendon sheaths, and bursas.

It presents in two forms: diffuse and localized.

The localized form is usually a single pedunculated mass or, less frequently, two or three nodules.

Histologically there is active proliferation of fibroblastic and histiocytic elements, showing macrophagic activity with phagocytosis of blood pigment (hemosiderin) and lipids.

Editor's note: Per the 2020 WHO Soft Tissue and Bone Tumors Classification (5th ed.), the recommended terminology is tenosynovial giant cell tumor with pigmented villonodular synovitis no longer recommended (although remains in common use).

How to use cases

You can use Radiopaedia cases in a variety of ways to help you learn and teach.

Creating your own cases is easy.

Updating… Please wait.

 Unable to process the form. Check for errors and try again.

 Thank you for updating your details.