Mesial temporal sclerosis

Case contributed by Vinay V Belaval
Diagnosis almost certain

Presentation

Epilepsy with fresh episode of seizure

Patient Data

Age: 40 years
Gender: Female
mri

Coronal T2w, axial T2w, and FLAIR images of temporal lobes show volume loss of the right hippocampus with T2 & FLAIR hyperintense signals. There is a loss of right hippocampal digitations. These features are consistent with right mesial temporal sclerosis.

The left hippocampus appears normal in volume and shows normal signals.

No other epileptogenic lesion was seen in the rest of the brain parenchyma.

Case Discussion

Mesial temporal sclerosis (MTS) is one of the common causes of intractable epilepsy. Patients often present with seizures, predominantly complex partial seizure patterns. MRI brain with epilepsy protocol should be done in all patients with seizures.

MRI shows classical features of mesial temporal sclerosis in the form of volume loss, loss of hippocampal digitations, and T2w & FLAIR hyperintense signals.

MTS can be bilateral in up to 3-10% of patients. Always look for a dual epileptogenic lesion in the rest of the brain, as 10-15% of patients with seizures can have dual pathology.

How to use cases

You can use Radiopaedia cases in a variety of ways to help you learn and teach.

Creating your own cases is easy.

Updating… Please wait.

 Unable to process the form. Check for errors and try again.

 Thank you for updating your details.