Mesial temporal sclerosis
Updates to Case Attributes
Mesial temporal sclerosis (MTS) is one of the common causes forof intractable epilepsy. Patients often present with seizures, predominantly complex partial seizure patternpatterns. MRI brain with epilepsy protocol should be done in all patients presenting with seizures.
MRI shows classical features of mesial temporal sclerosis in the form of volume loss, loss of hippocampal digitations, and T2w & FLAIR hyperintense signals.
MTS can be bilateral in uptoup to 3-10% of patients. Always look for a dual epileptogenic lesion in the rest of the brain, as 10-15% of patients with seizures can have dual pathology.
-<p>Mesial temporal sclerosis (MTS) is one of the common causes for intractable epilepsy. Patients often present with seizures, predominantly complex partial seizure pattern. MRI brain with epilepsy protocol should be done in all patients presenting with seizures.</p><p>MRI shows classical features of mesial temporal sclerosis in the form of volume loss, loss of hippocampal digitations and T2w & FLAIR hyperintense signals.</p><p>MTS can be bilateral in upto 3-10% of patients. Always look for dual epileptogenic lesion in rest of the brain, as 10-15% patients with seizures can have dual pathology.</p>- +<p>Mesial temporal sclerosis (MTS) is one of the common causes of intractable epilepsy. Patients often present with seizures, predominantly complex partial seizure patterns. MRI brain with epilepsy protocol should be done in all patients with seizures.</p><p>MRI shows classical features of mesial temporal sclerosis in the form of volume loss, loss of hippocampal digitations, and T2w & FLAIR hyperintense signals.</p><p>MTS can be bilateral in up to 3-10% of patients. Always look for a dual epileptogenic lesion in the rest of the brain, as 10-15% of patients with seizures can have dual pathology.</p>
References changed:
- 2. Henry T, Chupin M, Lehéricy S et al. Hippocampal Sclerosis in Temporal Lobe Epilepsy: Findings at 7 T. Radiology. 2011;261(1):199-209. <a href="https://doi.org/10.1148/radiol.11101651">doi:10.1148/radiol.11101651</a> - <a href="https://www.ncbi.nlm.nih.gov/pubmed/21746814">Pubmed</a>
- 1. Dekeyzer S, De Kock I, Nikoubashman O et al. “Unforgettable” – a Pictorial Essay on Anatomy and Pathology of the Hippocampus. Insights Imaging. 2017;8(2):199-212.
- 2. Henry T, Chupin M, Lehéricy S et al. Hippocampal Sclerosis in Temporal Lobe Epilepsy: Findings at 7 T. Radiology. 2011;261(1):199-209.
- 2. Henry T, Chupin M, Lehéricy S et al. Hippocampal Sclerosis in Temporal Lobe Epilepsy: Findings at 7 T. Radiology. 2011;261(1):199-209.
Updates to Study Attributes
Coronal T2w, axial T2w, and FLAIR images of temporal lobes show volume loss of the right hippocampus with T2 & FLAIR hyperintense signals. There is a loss of right hippocampal digitations.These. These features are consistent with right mesial temporal sclerosis.
LeftThe left hippocampus appears normal in volume and shows normal signals.
No other epileptogenic lesion was seen in the rest of the brain parenchyma.
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