Posterior reversible encephalopathy syndrome (PRES)

Case contributed by Vinay V Belaval
Diagnosis certain

Presentation

Delivery 2 days ago. Headache with seizures. Postpartum eclampsia.

Patient Data

Age: 20 years
Gender: Female

There are symmetrical T2 & FLAIR hyperintense signals in bilateral parieto-occipital lobes and bilateral high frontal lobes involving cortex and juxtacortical white matter with focal areas of facilitated diffusion. No blooming. No mass effect.

MR venogram showed normal appearance of dural venous sinuses. 

These features are consistent with posterior reversible encephalopathy syndrome (PRES).

Case Discussion

PRES manifests as reversible vasogenic edema, predominantly involving parieto-occipital lobes. Frontotemporal lobes and cerebellar hemispheres can also be involved. It can occur at atypical sites like the basal ganglia and brainstem. It may also be asymmetrical in distribution. 

It is important to rule out ischemic stroke and dural venous sinus thrombosis

Another differential is reversible cerebral vasoconstriction syndrome.

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