Primary pancreatic neuroblastoma

Case contributed by Ammar Haouimi , 6 Aug 2023
Diagnosis almost certain
Changed by Ammar Haouimi, 2 Oct 2023
Disclosures - updated 15 Sep 2023: Nothing to disclose

Updates to Case Attributes

Status changed from draft to published (public).
Published At was set to 2023-10-02T14:42:52.681Z.
Body was changed:

MRI features of bilobulated mass of the pancreatic tail in a child with a history of left nephrectomy with chemotherapy for nephroblastoma. This mass is atypical for intrapancreatic accessory spleen (pancreatic metastasis ? other ?).

An ultrasound-guided biopsy of the pancreatic mass was performed with a histopathological exam that confirmed the diagnosis of primary pancreatic neuroblastoma.

Neuroblastomas are the most common extracranial solid childhood malignancy and the third most common childhood tumour after leukaemia and brain malignancies. Around 30-35% of neuroblastomas are of extra-adrenal location in the retroperitoneum 1.

Primary pancreatic neuroblastoma is rare in children and only very few cases were reported in the literature1,2.

Additional contributor: ZE. Boudiaf, MD, CIM Aurès, Batna, Batna

  • -<p>MRI features of bilobulated mass of the pancreatic tail in a child with a history of left nephrectomy with chemotherapy for <a href="/articles/wilms-tumour" title="Nephroblastoma">nephroblastoma</a>. This mass is atypical for <a href="/articles/intrapancreatic-accessory-spleen" title="Intrapancreatic accessory spleen">intrapancreatic accessory spleen</a> (pancreatic metastasis ? other ?).</p><p>An ultrasound-guided biopsy of the pancreatic mass was performed with a histopathological exam that confirmed the diagnosis of primary pancreatic <a href="/articles/neuroblastoma" title="Neuroblastoma">neuroblastoma</a>.</p><p>Neuroblastomas are the most common extracranial solid <a href="/articles/childhood-malignancies">childhood malignancy</a> and the third most common childhood tumour after leukaemia and brain malignancies. Around 30-35% of neuroblastomas are of extra-adrenal location in the retroperitoneum <sup>1</sup>.</p><p>Primary pancreatic neuroblastoma is rare in children and only very few cases were reported in the literature.</p><p></p><p>Additional contributor: ZE. Boudiaf, MD, CIM Aurès, Batna, Batna</p>
  • +<p>MRI features of bilobulated mass of the pancreatic tail in a child with a history of left nephrectomy with chemotherapy for <a href="/articles/wilms-tumour" title="Nephroblastoma">nephroblastoma</a>. This mass is atypical for <a href="/articles/intrapancreatic-accessory-spleen" title="Intrapancreatic accessory spleen">intrapancreatic accessory spleen</a> (pancreatic metastasis ? other ?).</p><p>An ultrasound-guided biopsy of the pancreatic mass was performed with a histopathological exam that confirmed the diagnosis of primary pancreatic <a href="/articles/neuroblastoma" title="Neuroblastoma">neuroblastoma</a>.</p><p>Neuroblastomas are the most common extracranial solid <a href="/articles/childhood-malignancies">childhood malignancy</a> and the third most common childhood tumour after leukaemia and brain malignancies. Around 30-35% of neuroblastomas are of extra-adrenal location in the retroperitoneum <sup>1</sup>.</p><p>Primary pancreatic neuroblastoma is rare in children and only very few cases were reported in the literature <sup>1,2</sup>.</p><p></p><p>Additional contributor: ZE. Boudiaf, MD, CIM Aurès, Batna, Batna</p>

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