Prostate cancer with metastatic lymph nodes

Case contributed by Shervin Sharifkashani , 19 Mar 2022
Diagnosis almost certain
Changed by Daniel J Bell, 3 May 2022
Disclosures - updated 3 May 2022: Nothing to disclose

Updates to Study Attributes

Findings was changed:

There are multiple and significantly enlarged lymph nodes in the para-aortic and left side external iliac and inguinal stations; these are more compatible with metastatic lymph nodes considering the size of the lymph nodes and a history of prostate cancer of the patient. Fat hernia in theFatty left sidesided inguinal hernia is also seen. No contrast agent was injected because of the patient's intolerance.

Updates to Case Attributes

Body was changed:

The incidence of metastatic iliac and para-aortic lymph nodes in prostate cancer is low butand considered a stage M1a and systemic disease disease and also affects the recurrence-free survival rate of the patients. MRI and CT scans have low sensitivity and specificity for diagnosis and the first choice imaging modality is molecular imaging for early diagnosis. In this particular case because of the patient's intolerance, no contrast agent was injected.

  • -<p>The <a href="/articles/incidence-1">incidence </a>of metastatic iliac and <a href="/articles/para-aortic-lymph-nodes-2">para-aortic lymph nodes</a> in <a href="/articles/prostate-cancer-staging-1">prostate cancer </a>is low but considered a <a href="/articles/prostate-cancer-staging-1">stage </a><a title="Prostate cancer (staging)" href="/articles/prostate-cancer-staging-1">M1a</a> and systemic disease and also affects the <a href="/articles/prostate-imaging-recurrence-reporting">recurrence-free survival rate</a> of the patients. MRI and CT scans have low sensitivity and specificity for diagnosis and the first choice imaging modality is <a href="/articles/positron-emission-tomography">molecular imaging </a>for early diagnosis. In this particular case because of the patient's intolerance, no contrast agent was injected.</p>
  • +<p>The <a href="/articles/incidence-1">incidence </a>of metastatic iliac and <a href="/articles/para-aortic-lymph-nodes-2">para-aortic lymph nodes</a> in <a href="/articles/prostate-cancer-staging-1">prostate cancer </a>is low and considered <a href="/articles/prostate-cancer-staging-1">stage </a><a href="/articles/prostate-cancer-staging-1">M1a</a> disease and affects the <a href="/articles/prostate-imaging-recurrence-reporting">recurrence-free survival rate</a> of the patients. MRI and CT scans have low sensitivity and specificity for diagnosis and the first choice imaging modality is <a href="/articles/positron-emission-tomography">molecular imaging </a>for early diagnosis. In this particular case because of patient intolerance, no contrast agent was injected.</p>

References changed:

  • 1. Murray J & Roach Iii M. Role of Para-Aortic Radiotherapy in the Management of Prostate Cancer. Clin Oncol (R Coll Radiol). 2020;32(3):189-98. <a href="https://doi.org/10.1016/j.clon.2019.12.007">doi:10.1016/j.clon.2019.12.007</a> - <a href="https://www.ncbi.nlm.nih.gov/pubmed/31980365">Pubmed</a>
  • 2. Jackson A, Sohaib S, Staffurth J et al. Distribution of Lymph Nodes in Men with Prostatic Adenocarcinoma and Lymphadenopathy at Presentation: A Retrospective Radiological Review and Implications for Prostate and Pelvis Radiotherapy. Clin Oncol (R Coll Radiol). 2006;18(2):109-16. <a href="https://doi.org/10.1016/j.clon.2005.09.006">doi:10.1016/j.clon.2005.09.006</a> - <a href="https://www.ncbi.nlm.nih.gov/pubmed/16523810">Pubmed</a>
  • 1. Murray J & Roach III M. Role of Para-Aortic Radiotherapy in the Management of Prostate Cancer. Clin Oncol. 2020;32(3):189-98. <a href="https://doi.org/10.1016/j.clon.2019.12.007">doi:10.1016/j.clon.2019.12.007</a> - <a href="https://www.ncbi.nlm.nih.gov/pubmed/31980365">Pubmed</a>
  • 2. Jackson A, Sohaib S, Staffurth J et al. Distribution of Lymph Nodes in Men with Prostatic Adenocarcinoma and Lymphadenopathy at Presentation: A Retrospective Radiological Review and Implications for Prostate and Pelvis Radiotherapy. Clin Oncol. 2006;18(2):109-16. <a href="https://doi.org/10.1016/j.clon.2005.09.006">doi:10.1016/j.clon.2005.09.006</a> - <a href="https://www.ncbi.nlm.nih.gov/pubmed/16523810">Pubmed</a>

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