Articles

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1,110 results found
Article

Inferior vena caval thrombosis

Inferior vena caval thrombosis is an essential diagnosis while evaluating any neoplastic lesion, or portal hypertension. It is also important to differentiate bland thrombus from tumor thrombus. Clinical features A patient can present with many features which include bilateral pedal edema Bu...
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Testicular cancer

Testicular cancers are the most common malignancy in men between the ages of 20 and 34 years. Epidemiology Testicular cancer is uncommon, accounting for less than 1% of all internal organ malignancies 2. The commonest histology of the tumor varies with the age of affected individuals. Over 90...
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Kaposiform hemangioendothelioma

Kaposiform hemangioendotheliomas are rare, locally invasive vascular tumors that often present in infancy, most commonly as an enlarging cutaneous mass 1,2. They are currently classified as distinct from tufted angiomas in the ISSVA classification of vascular anomalies. However, some consider it...
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Benign and malignant characteristics of breast lesions at ultrasound

Benign and malignant characteristics of breast lesions at ultrasound allow the classification as either malignant, intermediate or benign based on work published by Stavros et al. in 1995. Radiographic features Ultrasound Malignant characteristics (with positive predictive values) sonog...
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Ischemic colitis

Ischemic colitis refers to inflammation of the colon secondary to vascular insufficiency and ischemia. It is sometimes considered under the same spectrum as intestinal ischemia. The severity and consequences of the disease are highly variable. Epidemiology Ischemic bowel is typically a disease...
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Chordoma

Chordomas are uncommon malignant tumors of the axial skeleton that account for 1% of intracranial tumors and 4% of all primary bone tumors.  They originate from embryonic remnants of the primitive notochord (earliest fetal axial skeleton, extending from the Rathke's pouch to the tip of the cocc...
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Neuroblastoma

Neuroblastomas are tumors of neuroblastic origin. Although they may occur anywhere along the sympathetic chain, the vast majority arise from the adrenal gland. They represent the most common extracranial solid childhood malignancy and are the third commonest childhood tumor after leukemia and b...
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Meningeal hemangiopericytoma (historical)

Hemangiopericytomas of the meninges are rare tumors of the meninges, now considered to be an aggressive form of solitary fibrous tumors of the dura. They often present as large and locally aggressive dural masses, frequently extending through the skull vault. They are difficult to distinguish on...
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Malignant transformation

Malignant transformation is the term given to the process whereby either normal, metaplastic, or benign neoplastic tissue, becomes a cancer. The process usually occurs in a series of steps and the affected tissue gradually accumulates the genetic mutations that express a malignant phenotype. The...
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Adrenal metastasis

Adrenal metastases are the most common malignant lesions involving the adrenal gland. Metastases are usually bilateral but may also be unilateral. Unilateral involvement is more prevalent on the left side (ratio of 1.5:1). Epidemiology They are present at autopsy in up to 27% of patients with ...
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Ovarian-Adnexal Reporting and Data System Ultrasound (O-RADS US)

The Ovarian-Adnexal Reporting and Data System Ultrasound (O-RADS US) forms the ultrasound component of the Ovarian-Adnexal Reporting and Data System (O-RADS). This system aims to ensure that there are uniform unambiguous sonographic evaluations of ovarian or other adnexal lesions, accurately ass...
Article

Neoplasm

Neoplasms, also known as tumors, are pathological masses, caused by cells abnormally proliferating and/or not appropriately dying. Neoplasms may be either benign or malignant. Malignant neoplasms are synonymous with cancers. Benign neoplasms clear origin (unless very large) slow growth  usua...
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Basal cell carcinoma

A basal cell carcinoma (BCC) is one of the commonest non-melanocytic types of skin cancer.  Epidemiology Typically present in elderly fair-skinned patients in the 7th to 8th decades of life. There may be an increased male predilection. Associations Multiple basal cell carcinomas may be prese...
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Retiform hemangioendothelioma

Retiform hemangioendotheliomas or hobnail hemangioendotheliomas are intermediate locally aggressive and rarely metastasizing vascular neoplasms with a distinctive hobnail endothelial cell morphology. Epidemiology Retiform hemangioendotheliomas are rare with <100 cases reported in the literatur...
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Superscan

A superscan is an imaging appearance on a Tc-99m diphosphonate bone scan which occurs as a result of a high ratio of bone to soft tissue tracer accumulation. Intense osteoblastic activity in the bones causes diminished renal and background soft tissue uptake. Pathology Etiology This appearanc...
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Kimura disease

Kimura disease, also known historically as eosinophilic hyperplastic lymphogranuloma, is a rare benign inflammatory disease that characteristically manifests as enlargement of cervical lymph nodes and salivary glands. Epidemiology Kimura disease typically affects males (80%) between 20-40 year...
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Lung cancer (staging - IASLC 7th edition) (historical)

The IASLC (International Association for the Study of Lung Cancer) 7th edition lung cancer staging system was proposed in 2010 and has now been updated and superseded by the 8th edition, published in 2016. Small cell lung cancer (SCLC) and non-small cell lung cancer (NSCLC) used to be staged di...
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Primary cutaneous melanoma

Primary cutaneous melanoma is the most common subtype of melanoma, a malignant neoplasm that arises from melanocytes. Melanocytes predominantly occur in the basal layer of the epidermis but do occur elsewhere in the body. Primary cutaneous melanoma is by far the most common type of primary melan...
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Yttrium-90 ibritumomab tiuxetan

Yttrium-90 ibritumomab tiuxetan, also known by the trade name Zevalin (Acrotech Biopharma LLC, USA), is a theranostic radiopharmaceutical approved for the treatment of patients with relapsed or refractory low grade or follicular non-Hodgkin lymphoma (NHL). More specifically, it is a radioimmunot...
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Hypertrophic osteoarthropathy

Hypertrophic osteoarthropathy (HOA) is a syndrome characterized by a periosteal reaction of the long bones without an underlying bone lesion. There is a broad range of manifestations, although typically there is symmetrical involvement of the appendicular skeleton. Accompanying abnormal soft tis...

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