Questions

Using immunohistochemistry, dysembryoplastic neuroepithelial tumors (DNETs) are usually positive for all of the following EXCEPT:

Which of the following metabolites accumulates in patients with isocitrate dehydrogenase (IDH) mutations and results in an increased likelihood of seizures?

In a patient with a diagnosis of glioblastoma (GBM), which of the following are poor prognostic features?

Which of the following is a good prognostic factor for glioblastoma (GBM)?

Which of the following is NOT TRUE regarding this coronal T2-weighted MR image of rectal cancer:

A 50-year-old man presents with deteriorating memory over the last 3 months. He has a history of right eye rhabdomyosarcoma treated with surgery. No other known illnesses. He is investigated with an MRI of the brain. What is the most likely diagnosis?

Which of the following is true regarding this axial MR image of rectal cancer:

What is the correct term for this peripancreatic collection?

A 40-year-old man with end-stage renal disease on continuous ambulatory peritoneal dialysis (CAPD). which complication has occurred in this patient and shown on this selected enhanced CT image?

What is the most likely diagnosis on this axial T1-weighted image of the right elbow?

All the following may be considered as risk factors for tubo-ovarian abscess EXCEPT...

Historically, secondary glioblastomas were considered... 

The "dot in a circle" sign is a specific sign in magnetic resonance (MR) and ultrasound (US) imaging of what pathology?

Which of the following radioisotopes is a positron emitter?

Which of these is NOT a recognized cause of pulsatile tinnitus?

A patient has well-differentiated prostate cancer. Which of the following PET radiopharmaceuticals would give the most sensitive and specific imaging assessment?

A 65-year-old patient with an astrocytic tumor with necrosis is biopsied and the tumor is shown to be IDH1 R132H negative on immunohistochemistry. What is the likelihood that they harbor an alternative IDH1 or IDH2 mutation?

A 40-year-old male, with no prior history of a brain tumor, undergoes resection of a heterogeneous left frontal lobe tumor. Histology demonstrates an astrocytic tumor with necrosis and microvascular proliferation. Immunohistochemistry confirms astrocytic differentiation and is negative for IDH1 R132H mutations. How should this tumor be classified?

Which of the following central nervous system cell types are NOT considered to be a type of glial cell?

Which of the following histological features is characteristic of dysembryoplastic neuroepithelial tumor (DNET)?