Articles

Articles are a collaborative effort to provide a single canonical page on all topics relevant to the practice of radiology. As such, articles are written and continuously improved upon by countless contributing members. Our dedicated editors oversee each edit for accuracy and style. Find out more about articles.

319 results found
Article

Hematoxylin and eosin stain

The combined hematoxylin and eosin (H&E) stain is the most widely used stain in histology and histopathology. Hematoxylin has an intense purple-blue hue and binds to nucleic acids. Eosin has a pink hue and non-specifically stains proteins. These two stains in combination are vital for distinguis...
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Gram stain

The Gram stain (or Gram method) is a key microbiological method for staining bacteria. The process relies upon two stains, the first, a complex of crystal violet and iodine, and the second, safranin, a red counterstain. The staining procedure subdivides bacteria into Gram-positive and Gram-negat...
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Hematinics

The hematinics are nutrients that are required by the body for erythropoiesis, i.e. the production of red blood cells 1,2. List of hematinics Clinically, the most important hematinics are vitamin B12, iron and folic acid because deficiency states of these three substances are much more common ...
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Red blood cells

Red blood cells (RBCs), also known as erythrocytes (or rarely haematids), are cells that carry oxygen by means of hemoglobin, and form part of the cellular component of blood as it circulates throughout the body. These extremely common cells are typically made in the bone marrow in a process cal...
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Corpora amylacea

The corpora amylacea ("bodies of starch") are a histologic finding, encountered more frequently in the brain, prostate, lung, and uterus. The corpora amylacea are thought to be sulfated glycosaminoglycans 1. Some have described it as a localized amyloidosis 2.  In the prostate they appear to ar...
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Inflammatory markers

The inflammatory markers are a disparate set of biomarkers that are used clinically to assess a patient for: presence/absence of an active inflammatory disease process activity of a known disease Possible disease processes may include infective, malignant and autoimmune diseases, although it ...
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Syndemic

A syndemic is a relatively novel concept in epidemiology, referring to the simultaneous occurrence and synergy of two or more diseases or conditions in a large population in a social context that aggravates them. A syndemic is usually confined to a certain geographical area at a certain time an...
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Metachronous (pathology)

The term metachronous is used in oncology to refer to two (or more) independent primary malignancies, when the second (or third, etc.) malignancy arose more than six months after the diagnosis of the first malignancy 1,2. These may be in the same, or in different, organs. See also synchronous ...
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Synchronous (pathology)

The term synchronous is used in oncology to refer to two (or more) independent primary malignancies, when the second (or third, etc.) malignancy arose within six months of the diagnosis of the first malignancy 1,2. These may be in the same, or in different, organs. See also metachronous multi...
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Endemic

The epidemiological term endemic is used for any condition that persists within a particular community/locale without the need for external input of new disease, i.e. the disease in question has attained a steady-state in the affected population 1. For this to happen the basic reproductive numbe...
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Epidemic

The epidemiological term, epidemic is defined for a condition that is normally rare in a population but in a short space of time has become widespread 1. It may refer to both infectious diseases (for example, Zika virus epidemic in Brazil 6) but also other conditions, e.g. the obesity epidemic. ...
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Pandemic

The epidemiological term, pandemic is applied to an outbreak of disease that has spread across the globe, or in other words, an epidemic that has crossed many regions, borders and multiple continents. Some of the largest pandemics in history include the bubonic plague in the 14th century and the...
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Host (infectious diseases)

A host in the context of infectious disease refers to an animal or plant that acts as a biological refuge in which another - often parasitic - organism may dwell. The host usually provides shelter or nourishment to the other organism, which may use the host to partially/completely sexually devel...
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Basic reproduction number

The basic reproduction number (R0), also known as just the reproductive number, basic reproductive number, basic reproductive ratio, reproduction number, R nought or R zero, is a term in epidemiology for the average number of cases in a susceptible population that will be generated by an existin...
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Incubation period

The epidemiological term, the incubation period (IP) is the time between exposure to something pathogenic (including radiation, microbes or chemicals) and when the pathology first becomes apparent by symptoms. Some authors use the terms latent period and incubation period to mean the same period...
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Vector (infectious disease)

A vector, (also known as a biological vector) in the context of infectious diseases, is a carrier, in particular an animal, and most commonly an arthropod, that transmits the infective entity from one host to another 1. Often the infective agent undergoes some change as part of its normal life c...
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Congestion

Congestion is a pathological term referring to reduced blood flow out from tissues, which may be localized or systemic 1. Clinical presentation Congestion commonly presents with increased swelling and edema of tissues where blood flow is reduced. With prolonged congestion, the tissues may beco...
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Zoonosis

A zoonosis (plural: zoonoses), also known as a zoonotic disease, is an infectious disease in humans (the host) for which another vertebrate animal can be the vector. Some zoonoses have an additional vector besides the vertebrate e.g. R. rickettsii is carried by ticks on mammals. Viruses, bacteri...
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Angiotensin converting enzyme

Angiotensin converting enzyme (ACE) is a central component of the renin-angiotensin system (RAS) which assists in blood pressure control by regulating the volume of fluids in the body. Normal individuals may have a small volume of the angiotensin converting enzyme circulating in their blood. M...
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Hamartoma

A hamartoma (plural: hamartomas or hamartomata) is a benign tumor-like malformation that consists of a collection of architecturally disorganized cells located in an area of the body where the cells are normally found. It is often due to abnormal development. In radiology, hamartomas often mimi...

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