Articles

Articles are a collaborative effort to provide a single canonical page on all topics relevant to the practice of radiology. As such, articles are written and continuously improved upon by countless contributing members. Our dedicated editors oversee each edit for accuracy and style. Find out more about articles.

318 results found
Article

Immunity

The human body regularly encounters harmful micro-organisms, and because of this it has developed a system of defenses to help identify and eliminate infective pathogens in the body, known as immunity, executed by the immune system. This system also contributes to antioncogenic mechanisms. Type...
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Embolism

Embolism describes intravascular material that is carried from its original location downstream to a distant area. The most common type of embolism is that which is derived from a thrombus, such as in the case of pulmonary embolism or stroke. Types of embolism thromboembolism gas embolism am...
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Inflammatory markers

The inflammatory markers are a disparate set of biomarkers that are used clinically to assess a patient for: presence/absence of an active inflammatory disease process activity of a known disease Possible disease processes may include infective, malignant and autoimmune diseases, although it ...
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Copper

Copper (chemical symbol Cu) is one of the trace elements. It has an important biological role as a redox agent and as a cofactor in cuproproteins, facilitating many vital metabolic reactions. Chemistry Basic chemistry Copper is a transition metal with the atomic number 29 and an atomic weight...
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Oxygen

Oxygen (chemical symbol O) is one of the basic organic elements, and is a constituent of most of the known organic molecules - and therefore all lifeforms - on earth.  Chemistry Basic chemistry Oxygen is a colourless odorless diatomic gas with an atomic number 8 and atomic weight 15.999. It h...
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Iodine

Iodine (chemical symbol I) is one of the trace elements. Its biological importance is its central place in the physiology of the thyroid gland and, in radiology, as the key chemical constituent of most of the radiographic, fluoroscopic, and CT contrast media. Chemistry Basic chemistry Iodine ...
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Hypersensitivity reaction

Hypersensitivity reactions are the immunological response to both exogenous and endogenous antigens, and form the basis for many diseases.  Pathology Classification Using the Gell and Coombs' classification, there are four types of hypersensitivity reactions, each mediated by a different mech...
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Homer Wright rosettes

Homer Wright rosettes are differentiated tumor cells grouped around a central region containing neuropil (therefore its association with tumors of neuronal origin). Pathology Examples of tumors where these can be seen include: medulloblastoma (the presence of Homer Wright rosettes in a poster...
Article

Streptococcus anginosus group

The Streptococcus anginosus group (also part of the Streptococcus milleri group) comprise a subgroup of viridans streptococci which are gram-positive, catalase-negative bacteria. There are three distinct main streptococcal species and several subspecies: S. anginosus: has two subspecies S. an...
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Aspergillus clavatus

Aspergillus clavatus is one of the species of Aspergillus that can cause pathology in humans. It is allergenic and causes a hypersensitivity pneumonitis called malt-workers lung. See also Aspergillus Aspergillus fumigatus Aspergillus flavus Aspergillus clavatus
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Decomposition

Decomposition of the human body occurs soon after death and is of relevance to radiology in the fields of postmortem and forensic radiology. Pathology Decomposition occurs due to two main processes 1,2: autolysis: degradation by destructive enzymes released by dying cells in the body putrefa...
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Alcian blue stain

Alcian blue stain is a histological stain utilized for the identification of extracellular matrix proteoglycans, like glycosaminoglycans and hyaluronic acid 1, commonly in connective tissue and epithelial malignant neoplasms 2, and also Barrett esophagus, where it can highlight mucosal intestina...
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Nestin

Nestin is an intermediate filament protein found primarily in central nervous system stem cells. It is the target of antibodies for immunohistochemistry for the assessment of neuropathological histology specimens. 
Article

Serum ascites albumin gradient

The serum–ascites albumin gradient (SAAG) is the difference between the concurrently obtained serum albumin concentration and the albumin concentration of the ascitic fluid obtained during paracentesis.  Pathology A difference ≥1.1 grams/deciliter (g/dL) indicates portal hypertension as the li...
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Corpora amylacea

The corpora amylacea ("bodies of starch") are a histologic finding, encountered more frequently in the brain, prostate, lung, and uterus. The corpora amylacea are thought to be sulfated glycosaminoglycans 1. Some have described it as a localized amyloidosis 2.  In the prostate they appear to ar...
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Anaplastic lymphoma kinase (ALK) gene rearrangements

Anaplastic lymphoma kinase (ALK) gene rearrangements are known to occur in association with several tumors. The genes code for an enzyme called anaplastic lymphoma kinase (ALK) or ALK tyrosine kinase receptor (also known as CD246) which is thought to play a role in brain development and exerts i...
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Giemsa stain

Giemsa stain is a commonly used histological stain that colors the cytoplasm blue to pink (depending on its acidity) and the nucleus blue to black 1. It serves as the diagnostic gold standard of histopathological staining of blood samples from patients with plasmodium-borne malaria, and as the b...
Article

14-3-3 protein

14-3-3 proteins are found in the cerebrospinal fluid (CSF) and are currently used to help identify patients with sporadic Creutzfeldt-Jakob disease (sCJD).  Seven distinct 14-3-3 proteins have been found in humans. In diagnosing sCJD, the sensitivity of 14-3-3 protein is 92%, and its specifici...
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Chemical article structure

Articles about chemicals, whether chemical elements or their innumerable compounds, have a unique structure and subheadings. All articles should be placed in the Pathology section. ======================================================================= The introduction should take the followin...
Article

Hypoplasia

Hypoplasia (plural: hypoplasias) is a pathological term referring to the state of a tissue or organ which at the end of its developmental process has not fully formed (cf. aplasia in which the organ/tissue does not form at all). Thus, the term hypoplasia does not tend to be used for a later (pos...

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