895 results found
Article
Li-Fraumeni syndrome
Li-Fraumeni syndrome is a hereditary cancer syndrome due to mutations in the tumor suppressor gene TP53. Approximately half of affected individuals are thought to develop invasive cancer by 30 years of age 1.
Associated malignancies
sarcomas
osteosarcoma
rhabdomyosarcoma
CNS tumors
gliomas...
Article
Lymphopenia
Lymphopenia (also known as lymphocytopenia, hypolymphemia and sublymphemia) is a deficiency of circulating lymphocytes 1. It may be either primary or secondary.
Terminology
The spelling lymphopaenia is erroneous and should never be used.
Pathology
Etiology
Primary
primary immunodeficienci...
Article
Lugano classification (PET-CT treatment response)
The Lugano classification is a lymphoma staging system for non-Hodgkin and Hodgkin lymphoma. This article outlines the classification's response to treatment based on PET-CT.
Also included in the classification are staging and response to treatment based on CT.
Scoring system
The Lugano clas...
Article
Haemophilic arthropathy
Haemophilic arthropathy refers to permanent joint disease occurring in hemophilia sufferers as a long-term consequence of repeated hemarthrosis.
Epidemiology
Around 50% of patients with hemophilia will develop severe arthropathy.
Clinical presentation
Presents similarly to osteoarthritis, w...
Case
Extramedullary hematopoiesis - presacral mass
Published
03 Sep 2021
81% complete
CT
MRI
Article
Autoimmune encephalitis
Autoimmune encephalitis, also known as autoimmune limbic encephalitis, is an antibody-mediated brain inflammatory process, typically involving the limbic system, although any part of the brain, and central nervous system more broadly, can be involved.
Autoimmune encephalitis can be divided broa...
Article
Hepatic lymphoma
Hepatic lymphoma is a term given to any form of hepatic involvement with lymphoma. This can be broadly divided into:
secondary hepatic involvement with lymphoma: most common by far, many tend to be non-Hodgkin lymphoma (NHL) 1
primary hepatic lymphoma: extremely rare
Pathology
Risk factors f...
Case
Cutaneous lymphoma
Published
04 Nov 2015
54% complete
Nuclear medicine
Photo
Case
Primary non-Hodgkin lymphoma of the duodenum
Published
07 Dec 2021
80% complete
CT
Case
Multiple myeloma
Published
04 Mar 2014
75% complete
CT
Case
Sickle cell spine
Published
22 May 2008
66% complete
X-ray
Article
Yttrium-90 ibritumomab tiuxetan
Yttrium-90 ibritumomab tiuxetan, also known by the trade name Zevalin (Acrotech Biopharma LLC, USA), is a theranostic radiopharmaceutical approved for the treatment of patients with relapsed or refractory low grade or follicular non-Hodgkin lymphoma (NHL). More specifically, it is a radioimmunot...
Case
Multiple myeloma (MRI)
Published
17 Jul 2011
89% complete
MRI
Case
Beta thalassemia major
Published
22 Jan 2015
75% complete
X-ray
Article
Diffuse large B-cell lymphoma
Diffuse large B-cell lymphoma (DLBCL) is the most common subtype of non-Hodgkin lymphoma.
Epidemiology
Associations
Diffuse large B-cell lymphoma is sometimes associated with immunodeficiency, including acquired immunodeficiency syndrome.
Pathology
Classification
In the 2016 WHO classifica...
Case
Primary renal lymphoma - hepatits C virus-associated
Published
09 Dec 2022
95% complete
MRI
Nuclear medicine
Ultrasound
Article
AIDS-related diffuse large B-cell lymphoma
AIDS-related diffuse large B-cell lymphomas are one of the immunodeficiency-associated CNS lymphomas, and in Western countries represented a dramatic increase in primary CNS lymphoma during the HIV/AIDS epidemic of the 1980s, although the incidence is likely lower in patients treated with antire...
Article
H-shaped vertebra
H-shaped vertebrae, also known as Lincoln log vertebrae, are a characteristic finding of sharply delimited central endplate depression, classically seen in approximately 10% of patients with sickle cell disease, and results from microvascular endplate infarction (Figure 1) 3.
It may occasionall...
Article
Graft versus host disease
Graft versus host disease (GvHD) is a frequent complication of allogeneic hematopoietic stem cell transplantation, commonly known as bone marrow transplantation. Antirejection drugs have reduced the incidence, although it does still frequently occur.
Pathology
Graft versus host disease can pr...
Article
Aplastic anemia
Aplastic anemia is a rare hematopoietic stem-cell disorder. The condition results in pancytopenia and hypocellular bone marrow. Most cases are acquired, however, there are unusual inherited forms.
Pathology
Aplastic anemia manifests as a marked reduction in the number of pluripotent hematopoie...
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