Articles

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104 results found
Article

Melanoma (staging)

Melanoma cancer staging refers to TNM classification of primary cutaneous melanoma. The system does not apply to the primary non-cutaneous melanomas. The following article reflects the 8th edition manual published by the American Joint Committee on Cancer (AJCC), which has been used for staging ...
Article

Thymic tumor (staging)

The thymic tumor staging using the TNM staging system only applies to the epithelial types including thymoma, thymic carcinoma, and neuroendocrine tumors of the thymus. It does not apply to thymic sarcoma, primary thymic lymphoma or other rare tumors. This staging system is based upon recommend...
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Akeret staging of neuroepithelial tumors

The Akeret or anatomical staging of neuroepithelial tumors adheres loosely to the general scheme underlying AJCC TNM staging. Like other cancer staging systems, it assists in estimating the individual prognosis, in tailoring patient-specific therapy and surveillance, and in improving the compara...
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Jewett-Strong-Marshall tumor staging system

Jewett-Strong-Marshall tumor staging system for bladder cancer is of historic interest only and has been superseded by the TNM staging system. stage 0: epithelial stage A: submucosal invasion but no involvement of muscle i.e. lamina propria stage B: bladder wall or muscle invasion B1: superf...
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Colorectal cancer (TNM staging 7th edition)

The 7th edition of the TNM classification of colorectal carcinomas was proposed in 2010, and has now been updated and replaced by the 8th edition, published in 2016. Primary tumor staging (T) Tx: primary tumor cannot be assessed T0: no evidence of primary tumor Tis: carcinoma in situ T1: in...
Article

Tumor pseudoprogression (lung cancer)

Radiologic tumor pseudoprogression on imaging denotes an imaging appearance of tumor response where the tumor first exhibits findings suggestive of progression (i.e. growth, new lesions). However, during sustained therapy, response is eventually demonstrated 1. Epidemiology With the advent of ...
Article

Gallbladder cancer (staging - AJCC 8th edition)

The AJCC (American Joint Committee on Cancer) 8th edition gallbladder cancer staging system was introduced in 2018. TNM system T: primary tumor Tis: carcinoma in situ - tumor only within the epithelium (the inner layer of the gallbladder) T1: tumor invades the lamina propria or muscularis T...
Article

Distal cholangiocarcinoma (staging)

Distal cholangiocarcinoma staging is defined according to the TNM staging classification of the American Joint Committee on Cancer (AJCC)/Union for International Cancer Control (UICC). As of 2018, the staging criteria are in their 8th edition and reflected below 1. These criteria apply to cancer...
Article

Perihilar cholangiocarcinoma (staging)

Perihilar cholangiocarcinoma staging is, for prognostication, most commonly conducted using the TNM staging classification of the American Joint Committee on Cancer (AJCC)/Union for International Cancer Control (UICC). As of 2018, the staging criteria are in their 8th edition and reflected below...
Article

Rectal cancer response assessment

Assessment of rectal cancer response to therapy, which may be chemotherapy, radiotherapy, or a combination, relies on the synthesis of clinical, endoscopic and radiologic evaluation.  The purpose of neoadjuvant therapy is to downstage the tumor, to facilitate surgical resection, and reduce loca...
Article

Skip metastases to the axillary lymph nodes in breast cancer

Skip metastases to the axillary lymph nodes in breast cancer refer to the uncommon phenomenon in which metastases do not follow the conventional stepwise pattern from level I to level II, to level III (infraclavicular), to the supraclavicular fossa, and or internal jugular chain 1-6,9. Terminol...
Article

Iannetti classification of orbital invasion

The Iannetti classification grades orbital invasion by ethmoido-orbital tumors, such as adenocarcinoma, squamous cell carcinoma, adenoid cystic carcinoma, undifferentiated carcinoma, sarcoma, or olfactory neuroblastoma. Classification grade I: erosion or destruction of the orbital medial wall ...
Article

Levene index

The Levene index or ventricular index is a marker of ventricular size in infants. It is defined as the distance between the falx and the lateral wall of the anterior horn of the lateral ventricle in the coronal plane 1.   Usage The Levene index is a marker of ventricular volume and thus can be...
Article

Chandler classification of orbital infections

Chandler classification is the most commonly used system for dividing the different types of orbital cellulitis. The system describes five stages 1,2: stage I: preseptal orbital cellulitis with inflammation and edema anterior to the orbital septum. stage II: orbital cellulitis with extension o...
Article

B symptoms

The B symptoms (a.k.a. inflammatory symptoms) are a triad of systemic symptoms associated with more advanced disease and a poorer outcome in lymphoma 1,2: weight loss >10% unintentional decrease in body weight in the 6 months preceding the diagnosis fever: >38°C night sweats B symptoms are ...
Article

Intrahepatic cholangiocarcinoma (staging)

Intrahepatic cholangiocarcinoma staging is conducted most commonly in accordance with the TNM staging classification of the American Joint Committee on Cancer (AJCC)/Union for International Cancer Control (UICC). As of 2018, the staging criteria are in their 8th edition and reflected below 1. Th...
Article

Neuroblastoma (image-defined risk factors)

Image-defined risk factors are imaging features seen at the time of neuroblastoma diagnosis that confer a poorer prognosis. The International Neuroblastoma Risk Group (INRG) suggested an update (2009) to the neuroblastoma staging with a list of features that, if present, upstages a patient with ...
Article

Esophageal and esophagogastric junction neuroendocrine tumor (staging)

Esophageal and esophagogastric junction neuroendocrine tumor staging refers to TNM staging of epithelial cancers other than the squamous cell carcinoma and adenocarcinoma groups located in the esophagus or esophagogastric junction (including tumors whose center is within the proximal 2 cm of the...
Article

Esophageal and esophagogastric junction adenocarcinoma (staging)

Esophageal and esophagogastric junction adenocarcinoma staging refers to TNM staging of adenocarcinoma originating in the esophagus or esophagogastric junction (including tumors whose center is within the proximal 2 cm of the gastric cardia). Related histologies included in this system are high...
Article

Medullary thyroid cancer (staging)

Medullary thyroid cancer staging refers to TNM staging of medullary thyroid carcinomas. Papillary, follicular, and anaplastic thyroid carcinomas have similar TNM category definitions but different prognostic stage group definitions. The following article reflects the 8th edition manual published...

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