Articles

Articles are a collaborative effort to provide a single canonical page on all topics relevant to the practice of radiology. As such, articles are written and continuously improved upon by countless contributing members. Our dedicated editors oversee each edit for accuracy and style. Find out more about articles.

359 results found
Article

Mastectomy

Mastectomy is a surgical treatment for breast cancer in which the entire breast tissue is removed through a surgical procedure as opposed to a wide local excision. Sometimes, adjacent structures, such as lymph nodes, are removed to prevent recurrence or metastasis. In some cases, mastectomy is d...
Article

Oncotype DX Breast Recurrence Score

Oncotype DX Breast Recurrence Score (Exact Sciences, USA) is a proprietary 21-gene expression assay that is prospectively validated and provides prognostic information on the 10-year risk of disease recurrence in estrogen receptor positive, lymph node-negative breast cancer patients 1. This gene...
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Usual ductal hyperplasia

Usual ductal hyperplasia, also known as epithelial hyperplasia, is a benign proliferation of normal cells in breast ducts and lobules. Epidemiology The mean age of patients with epithelial hyperplasia is 54 years 1. Clinical presentation Epithelial hyperplasia is usually asymptomatic and fou...
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Axillary web syndrome

Axillary web syndrome is a commonly occurring condition secondary to breast cancer surgery involving lymphadenectomy 1. It is characterized by the presence of one or multiple thin cords in the subcutaneous tissues of the axilla, which extends down the arm and/or chest wall 1,2. This can lead to ...
Article

Autoimmune/inflammatory syndrome induced by adjuvants

Autoimmune/inflammatory syndrome induced by adjuvants (ASIA syndrome) encompasses non-specific symptoms that occur following exposure to inert material (e.g. silicone, aluminum salts), which are thought to trigger an abnormal autoimmune response 1-3. Whether this is association or causation is s...
Article

Air-tissue interface sign - breast

Air-tissue interface sign on mammography in cases where the mass is located on the skin helps to distinguish it from intra-mammary mass so that in the skin-based lesion, due to the presence of air in the vicinity of a part of the margin, its border is pretty sharp and a narrow lucent rim around ...
Article

Normal imaging examples

This article lists examples of normal imaging divided by body region and system. brain head and neck spine chest breast gastrointestinal genitourinary hepatobiliary upper limb lower limb pediatrics
Article

Leave alone lesions - breast

Breast leave alone lesions are so characteristic on mammography that further diagnostic tests such as a biopsy are unnecessary. All of these lesions are entirely benign and known as BI-RADS 2 findings: lipoma: fat density; well-defined rounded lesion oil cyst: fat density; well-defined lesion;...
Article

Edematous breast

Edematous breast refers to the thickening of skin and Cooper's ligaments of the breast with increased parenchymal density on mammography, which causes a coarse reticular pattern. Findings could be unilateral or bilateral, and regarding the presence or absence of inflammation/erythema, differenti...
Article

Athelia

Athelia is a rare congenital condition characterized by the absence of the nipple. This may occur unilaterally or bilaterally. Associations Poland syndrome ectodermal dysplasia 2
Article

Flat epithelial atypia

Flat epithelial atypia is an entity that comprises any columnar cell lesion with low-grade cytologic atypia. Terminology Flat epithelial atypia was introduced in the 3rd edition of WHO Classification of Breast Tumors in 2003, to substitute terms such as clinging carcinoma monomorphous type, at...
Article

Columnar cell hyperplasia of the breast

Columnar cell hyperplasia is part of the spectrum of columnar cell lesions of the breast characterized by enlarged terminal ductal lobular units lined by stratified (more than two layers) columnar epithelium, cellular crowding or overlapping without atypia. It can also form tufts or mounds with...
Article

Columnar cell change without atypia (breast)

Columnar cell change without atypia breast lesions are characterized by enlarged terminal ductal lobular units lined by columnar epithelial cells which substitute the normal cuboid epithelial layer.  They are also associated with prominent apical cytoplasmic snouts and intraluminal secretions. ...
Article

Non-puerperal mastitis

Non-puerperal mastitis, also known as Zuska disease, Zuska-Atkins disease or squamous metaplasia of lactiferous ducts (SMOLD) is a rare benign breast condition that is characterized by recurrent subareolar abscess formation, sometimes followed by chronic fistula formation and pus drainage. It is...
Article

Inspissated secretions

Inspissated secretions refers to thickened secretions with increased viscosity within ducts or body cavities (usually nasal, paranasal sinus, oral or ductal) that usually become thickened by dehydration (typically a chronic process). The secretions can then cause obstruction to respective airway...
Article

Cyclin-dependent kinase 4 and 6 (CDK4/6) inhibitors

Cyclin-dependent kinase 4 and 6 (CDK4/6) inhibitors including palbociclib, ribociclib, and abemaciclib are used in patients with hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative (HR+/HER2−) advanced breast cancer. Another CDK inhibitor, trilaciclib, has be...
Article

Skip metastases to the axillary lymph nodes in breast cancer

Skip metastases to the axillary lymph nodes in breast cancer refer to the uncommon phenomenon in which metastases do not follow the conventional stepwise pattern from level I to level II, to level III (infraclavicular), to the supraclavicular fossa, and or internal jugular chain 1-6,9. Terminol...
Article

Pleural silicone granuloma

Pleural silicone granulomas result from an extremely rare situation where there is leakage of silicone from an implant rupture into the thorax.  Pathology It is thought that scars from remote thoracotomy may provide a potential pathway for ruptured silicone to fistulise into the pleural space....
Article

Mean glandular dose

The mean glandular dose (MGD) is an estimate of the average absorbed dose to the glandular tissues of a breast during mammography. It is measured in Gray (Gy). The most commonly accepted method of calculating the mean glandular dose is described by Dance et al (2000):                          ...
Article

K-absorption edge

The K-absorption edge (K-edge) refers to the abrupt increase in the photoelectric absorption of x-ray photons observed at an energy level just beyond the binding energy of the k-shell electrons of the absorbing atom. K-shell binding energies are specific to each element. As the atomic number (Z...

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