Articles

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1,950 results found
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Fabry disease

Fabry disease, also known as Anderson-Fabry disease, is a multisystem disorder resulting from an X-linked inborn error of metabolism and is a lysosomal storage disorder. The disease results from genetic mutations in the gene GLA that cause decreased or absent expression of hydrolase alpha-galact...
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Common carotid artery

The common carotid arteries (CCA) are paired branchless arteries of the neck that supply blood to the head, face and neck. Each common carotid bifurcates into internal and external carotid arteries. Summary origin: left: branch of the aortic arch right: branch of the brachiocephalic trunk c...
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Mumps

Mumps is a (usually) self-limited viral infection that often occurs in epidemics among children. Its incidence has markedly diminished in countries with childhood vaccination programs, but may still be seen in adult patients who have not received vaccinations or who have waning immunity. It may ...
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External auditory canal cholesteatoma

External auditory canal cholesteatomas are a rare subtype of acquired cholesteatoma. Epidemiology The external acoustic canal is a rare location for a cholesteatoma with an estimated incidence of around 1.2 per 1,000 new otological patients ref. The overall incidence rate in one large study wa...
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Benign enhancing foramen magnum lesion

Benign enhancing foramen magnum lesions, also described as high signal lesions, are an incidental finding on 3D FLAIR MRI in a typical location in the foramen magnum just posterior to the intradural vertebral artery.  Epidemiology The prevalence of this finding was 3% in a retrospective review...
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Carotidynia

Carotidynia, also known as Fay syndrome, is a rare syndrome characterized by neck pain in the region of the carotid bifurcation. It was classified by the International Headache Society (IHS) in 1988 as an idiopathic neck pain syndrome associated with tenderness over the carotid bifurcation with...
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Transsphenoidal hypophysectomy

Transsphenoidal hypophysectomy is a commonly used surgical approach for pituitary region masses, with many significant advantages over open craniotomy.  History The transsphenoidal approach was first described in 1907 by Schloffer, modified by Halstead and subsequently popularized by Harvey Cu...
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Pharyngeal plexus

The pharyngeal plexus lies on the posterolateral wall of the pharynx, mainly over the middle pharyngeal constrictor and is the main motor and sensory nerve supply to the muscles of the pharynx and soft palate and acts to coordinate swallowing and speech 1-7. Summary location: within the extern...
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Incisivus labii inferioris muscle

The incisivus labii inferioris muscle (TA: pars labialis musculi orbicularis oris) is one of the facial muscles. It acts as a supplementary muscle to the orbicularis oris muscle. Terminology The incisivus labii inferioris muscle is often omitted from major anatomical texts or articles on the f...
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Thyroid malignancies

Thyroid malignancies are most commonly primary thyroid cancers but can rarely be metastatic deposits. Epidemiology Risk factors head and neck irradiation (see radiation-induced thyroid cancer) family history of thyroid cancer age <30 or >60 years male >2 cm  Pathology Classification Th...
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Eagle syndrome

Eagle syndrome refers to symptomatic elongation of the styloid process or calcified stylohyoid ligament 1,2. It is often bilateral. In most cases, the cause is unknown; however, the condition is sometimes associated with disorders causing heterotopic calcification such as abnormal calcium/phosph...
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Fissula ante fenestram

The fissula ante fenestram (plural: fissula ante fenestras) is a small connective tissue-filled cleft in the otic capsule of the temporal bone, not typically visible on CT. The area around the fissula ante fenestram is the usual origin of fenestral otosclerosis. Gross anatomy The fissula ante ...
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Leptomeningeal cyst

Leptomeningeal cysts, also known as growing skull fractures, are an enlarging skull fracture that occurs near post-traumatic encephalomalacia. The term cyst is actually a misnomer, as it is not a cyst, but an extension of the encephalomalacia. Hence, it is usually seen a few months post-trauma. ...
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Riedel thyroiditis

Riedel thyroiditis is a very rare form of autoimmune thyroiditis. It is sometimes considered as a manifestation of a wider systemic disease with fibrosis of the retroperitoneum, mediastinum, as well as lymphocytic infiltration of extraocular orbital muscles, salivary and lacrimal glands 4. All t...
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Psammoma bodies

Psammoma bodies are round microscopic calcific collections. It is a form of dystrophic calcification. Necrotic cells form the focus for surrounding calcific deposition. They have a lamellated concentric calcified structure, sometimes large enough to be seen on CT.  Psammoma bodies are found in ...
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Carotid artery stenosis

Carotid artery stenosis, also known as extracranial carotid artery stenosis, is usually caused by an atherosclerotic process and is one of the major causes of stroke and transient ischemic attack (TIA).  This article refers to stenosis involving the carotid bulb and the proximal segment of inte...
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Optic nerve sheath meningioma

Optic nerve meningiomas are benign tumors arising from the arachnoid cap cells of the optic nerve sheath and represent ~20% of all orbital meningiomas, the majority of which are direct extensions from intracranial meningiomas.  These tumors typically appear as masses within the optic nerve, iso...
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Squamous cell carcinoma (oral cavity)

Squamous cell carcinoma of the oral cavity is the most common (by far) of the malignant lesions affecting this region.  As they share epidemiology, pathology and general principles with other squamous cell carcinomas of the upper aerodigestive tract, those topics are covered there. Below are a ...
Article

Parathyroid adenoma

Parathyroid adenomas are benign tumors of the parathyroid glands and are the most common cause of primary hyperparathyroidism. Epidemiology Associations There is an association with multiple endocrine neoplasia types I (MEN1) and IV (MEN4). Clinical presentation Patients typically present w...
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Progressive multifocal leukoencephalopathy

Progressive multifocal leukoencephalopathy (PML) is a demyelinating disease which results from the reactivation of John Cunningham virus (JC virus) infecting oligodendrocytes in patients with compromised immune systems. It is considered the most common clinical manifestation of JC virus infecti...

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