Articles
Articles are a collaborative effort to provide a single canonical page on all topics relevant to the practice of radiology. As such, articles are written and continuously improved upon by countless contributing members. Our dedicated editors oversee each edit for accuracy and style. Find out more about articles.
336 results found
Article
Lymphomatoid granulomatosis
Lymphomatoid granulomatosis, also known as angiocentric lymphoma or angiocentric immunoproliferative lesion, is a rare type of non-Hodgkin lymphoma associated with Epstein-Barr virus infection.
Pathology
There is a recognized association with antecedent infection with the Epstein-Barr virus (...
Article
Lymphomatoid granulomatosis (pulmonary manifestations)
Pulmonary manifestations of lymphomatoid granulomatosis are important since the lung is one of the most frequent sites of involvement in lymphomatoid granulomatosis. It falls under the group of pulmonary angiitis and granulomatosis.
Pathology
Some consider the condition to be midway between ov...
Article
Hodgkin lymphoma
Hodgkin lymphoma or Hodgkin disease (HD) is a type of lymphoma and accounts for ~1% of all cancers. Hodgkin disease spreads contiguously and predictably along lymphatic pathways and is curable in ~90% of cases, depending on its stage and subtype.
Epidemiology
There is a bimodal distribution in...
Article
Splenunculus
Splenunculi, also known as supernumerary spleens, accessory spleens, or splenules, are small nodules of spleen that are separate from the rest of the organ.
Epidemiology
They are common, seen in up to 16% of CTs of the abdomen and up to 30% of autopsies 2.
Pathology
Accessory spleens are c...
Article
Light chain amyloidosis
Amyloid light chain (AL) amyloidosis or immunoglobulin light chain amyloidosis is a systemic amyloidosis and a plasma cell proliferative disorder characterized by deposition of misfolded monoclonal kappa or lambda light chains produced by clonal plasma cells 1-6.
Epidemiology
Amyloid light cha...
Article
Multiple myeloma
Multiple myeloma (MM), also known as plasma cell myeloma, is a multifocal proliferation of plasma cells based in the bone marrow. It is the most common primary malignant bone neoplasm in adults. It arises from red marrow due to the monoclonal proliferation of plasma cells and manifests in a wide...
Article
Leukemoid reaction
A leukemoid reaction refers to a marked increase in white blood cells (>50000 cells/mL), typically neutrophils, which manifests as an acute inflammatory reaction that can mimic leukemia.
Pathology
Leukemoid reactions often occur from accelerated release of cells from the bone marrow.
Features...
Article
Leukemia
Leukemia is a hematological neoplasm characterized by the overproduction of immature (blasts) or abnormally differentiated cells of the hematopoietic system in the bone marrow that often, but not always, extends into the peripheral blood.
This article aims to provide an overview of leukemia as...
Article
Pulmonary Pneumocystis jirovecii infection
Pulmonary Pneumocystis jirovecii infection, also known as Pneumocystis jirovecii pneumonia (PJP) or Pneumocystis pneumonia (PCP), is an atypical pulmonary infection and the most common opportunistic infection in patients with acquired immunodeficiency syndrome (AIDS).
Terminology
Classically, ...
Article
Paraneoplastic cerebellar degeneration
Paraneoplastic cerebellar degeneration is a type of paraneoplastic syndrome, and manifestation of autoimmune encephalitis, characterized by the progressive onset of cerebellar dysfunction not explained by tumoral invasion, metastasis, or treatment side effects.
Clinical presentation
Cerebellar...
Article
Haemophilic arthropathy
Haemophilic arthropathy refers to permanent joint disease occurring in hemophilia sufferers as a long-term consequence of repeated hemarthrosis.
Epidemiology
Around 50% of patients with hemophilia will develop severe arthropathy.
Clinical presentation
Presents similarly to osteoarthritis, w...
Article
Evans syndrome
Evans syndrome is an autoimmune condition with two or more cytopenias, usually caused by autoimmune hemolytic anemia (AIHA) and immune thrombocytopenia (ITP), with or without immune neutropenia.
Epidemiology
Evans syndrome is considered rare, with defining bicytopenias present in less than 5% ...
Article
Acute myeloid leukemia
Acute myeloid leukemia (AML), also referred to as acute myelogenous leukemia, is a hematological malignancy characterized by the abnormal clonal proliferation of immature myeloid precursors (myeloblasts) or poorly differentiated cells of the hematopoietic system. It primary infiltrates the bone ...
Article
Eosinophilia
Eosinophilia is defined as an abnormally high level of eosinophils in the blood, this is usually defined as >500 cells/μL (normal eosinophil level: <450 cells/μL). Hypereosinophilia is defined as >1500 cells/μL and is usually due to hematological malignancy 1,2.
This article includes recommenda...
Article
Notch sign (primary CNS lymphoma)
The notch sign refers to an abnormally deep depression at the tumor margin in contrast-enhanced MRI in primary CNS lymphoma 1. It is not an uncommon sign in primary CNS lymphoma and can be seen in both immunocompetent and immunocompromised patients. It suggests an irregular growth pattern as wel...
Article
Ann Arbor staging system (historical)
The Ann Arbor staging system was the landmark lymphoma staging classification system for both Hodgkin lymphoma and non-Hodgkin lymphoma. It is named after the town of Ann Arbor in the US state of Michigan where the Committee on Hodgkin's Disease Staging Classification met in 1971 to agree on it....
Article
Lederer-Brill disease
Lederer-Brill disease is a transient autoimmune hemolytic anemia with very variable clinical features 1.
Epidemiology
Lederer-Brill disease is slightly more prevalent in females 1.
Clinical presentation
It usually occurs in children with a recent history of infection. Symptoms and signs incl...
Article
Gallbladder lymphoma
Gallbladder lymphoma is exceedingly rare and presents diagnostic challenges due to its imaging characteristics often resembling those of gallbladder adenocarcinoma.
Epidemiology
Primary lymphomas of the gallbladder are extremely rare, accounting for approximately 0.1-0.2% of all malignant tumo...
Article
Extramedullary hematopoiesis
Extramedullary hematopoiesis is a response to the failure of erythropoiesis in the bone marrow.
This article aims to a general approach on the condition, for a dedicated discussion for a particularly involved organ, please refer to the specific articles on:
extramedullary hematopoiesis in the...
Article
Splenic biopsy
Percutaneous splenic biopsy, using either ultrasound or CT guidance, is an accurate and reliable method of acquiring splenic tissue for histopathological assessment and has been proposed as an alternative for splenectomy in selected patients.
Although the procedure has been historically feared ...
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