Articles
Articles are a collaborative effort to provide a single canonical page on all topics relevant to the practice of radiology. As such, articles are written and continuously improved upon by countless contributing members. Our dedicated editors oversee each edit for accuracy and style. Find out more about articles.
337 results found
Article
Sézary syndrome
Sézary syndrome (SS) is a type of primary cutaneous T-cell lymphoma.
Clinical presentation
It is clinically characterized by an extensive erythematous rash covering most of the body as well as the presence of malignant lymphocytes in the blood.
History and etymology
It is named after Albert...
Article
Pancreatic lymphoma
Pancreatic lymphoma is most commonly a B-cell subtype of non-Hodgkin lymphoma
Epidemiology
Pancreatic lymphoma is typically seen in middle-aged patients with a mean age of around 55 years old and is more common in immunocompromised patients.
Clinical presentation
Symptoms are often non-speci...
Article
Primary ovarian lymphoma
Primary ovarian lymphoma (POL) refers to the involvement of the ovary with lymphoma but without the involvement of any other site. It is an extremely rare yet well-recognized condition.
Epidemiology
Primary ovarian lymphoma accounts for ~1.5% of ovarian tumors 5.
Pathology
The rarity of this...
Article
Lugano staging classification
The Lugano staging classification is the lymphoma staging system that is most commonly used in clinical practice currently. The categories for initial staging are defined in this article. See separate articles for the Lugano criteria for response assessment by PET-CT or by CT alone, as well as g...
Article
Myelodysplastic syndrome
Myelodysplastic syndromes (MDS) are a heterogeneous group of clonal hematological stem cell disorders characterized by dysplasia and ineffective hematopoiesis. It carries a risk of transformation to acute leukemia.
Epidemiology
Its overall incidence is thought to be around 3.3 per 100,000. The...
Article
Apheresis
Apheresis is an extracorporeal procedure in which the main components of blood (red blood cells, plasma, and plasma proteins) are separated and removed from the body. It is used as therapeutic measure for certain conditions.
Radiological implications
It is one of the indications of placement o...
Article
T-prolymphocytic leukemia
T-prolymphocytic leukemia (T-PLL) is a rare and unusual hematological malignancy.
Terminology
In the WHO classification, this is referred to as T-prolymphocytic leukemia rather than T-cell prolymphocytic leukemia.
Epidemiology
It represents around 2% of all mature lymphocytic leukaemias in a...
Article
Anion gap metabolic acidosis causes (mnemonic)
A mnemonic to remember the commonest causes of anion gap metabolic acidosis is:
GOLDMARK
Mnemonic
G: glycols (ethylene glycol and propylene glycol)
O: oxoproline
L: L-lactate
D: D-lactate
M: methanol
A: aspirin
R: renal failure
K: ketoacidosis
Article
Primary hepatic lymphoma
Primary hepatic lymphoma (PHL) is very rare, with approximately 100 described cases. If it is being considered as a diagnosis, distant lymphadenopathy, splenomegaly, bone marrow disease, and leukemia should not be present for at least 6 months after the liver tumor has been detected (see: second...
Article
Transient abnormal myelopoiesis
Transient abnormal myelopoiesis (TAM) is a phenomenon that can happen in the fetuses or neonates with trisomy 21. The condition can mimic leukemia.
Epidemiology
The estimated incidence is at ~10% of newborns with trisomy 21 3.
Radiographic features
Antenatal ultrasound
In the context of kno...
Article
Reticuloendothelial system
The reticuloendothelial system (RES) comprises a number of tissues:
spleen
bone marrow
liver Kupffer cells
Article
Large bowel lymphoma
Large bowel (colorectal) lymphoma is a very rare tumor, accounting for <0.5% of primary colorectal malignancies, ~1.5% of all lymphomas, and ~15% of gastrointestinal lymphomas. Large bowel lymphoma differs from gastric and small bowel lymphoma in clinical presentation, management, and prognosis....
Article
Lugano classification (response to treatment on CT)
The Lugano classification is a lymphoma staging system resulting from recommended changes in 2011 to the Ann Arbor staging with Cotswolds modifications. This article outlines the classification's response to treatment based on CT.
Also included in the classification are staging and response to...
Article
Thrombocytopenia causes (mnemonic)
A mnemonic to remember the commonest causes of thrombocytopenia is:
PLATELETS
Mnemonic
P: platelet disorders (DIC, TTP, ITP)
L: leukemia
A: anemia
T: trauma
E: enlarged spleen
L: liver disease
E: ethanol
T: toxicity (heparin, aspirin, chemotherapy, benzene)
S: sepsis
Article
Felty syndrome components (mnemonic)
Felty syndrome is a rare condition that involves rheumatoid arthritis, decreased white blood cell count and spleen enlargement.
A mnemonic to remember the basic components of Felty syndrome is:
SANTA
Mnemonic
S: splenomegaly
A: anemia
N: neutropenia
T: thrombocytopenia
A: arthritis (rhe...
Article
Hemochromatosis
Hemochromatosis is an iron overload disorder characterized by a progressive increase in total body iron stores and deposition of iron in some non-reticuloendothelial system (RES) body organs which results in some instances of organ dysfunction.
This article focuses on the general principles of ...
Article
Lymphoma of the spinal cord
Lymphoma of the spinal cord is an uncommon manifestation of lymphoma. Although lymphoma more commonly involves the vertebral body (vertebral body tumors) or epidural compartment, intramedullary lymphoma may rarely occur.
Apparent intramedullary spinal cord lymphoma may often, in fact, represe...
Article
Pulmonary artery stump thrombosis
Pulmonary artery stump thrombosis describes thrombus formation occurring at the site of the pulmonary arterial stump, a complication following lobectomy or pneumonectomy. It is usually discovered as an incidental finding on routine follow-up chest CT scans.
Epidemiology
The prevalence of pulmo...
Article
Tumors associated with increased erythropoetin
Tumors associated with increased erythropoetin are varied and numerous. Patients will be polycythemic due to erythropoetin secretion. Tumors in this group include:
renal cell carcinoma (RCC) 2
hepatocellular carcinoma (HCC)
hemangioblastoma
Article
Anemia
Anemia is the presence of reduced hemoglobin in the blood. Formally, the World Health Organizatiοn (WHO) defines anemia by the hemoglobin concentration in the blood according to age and sex 1:
adult men: <130 g/L
adult women: <120 g/L
Values for pregnant women and children are different.
Cli...