Articles

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1,114 results found
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Whole-body diffusion-weighted MRI

Whole-body diffusion-weighted MRI (WB-MRI) is an advanced imaging technique that combines anatomical and functional MRI sequences to provide a comprehensive assessment of the whole-body in a single examination. WB-MRI uses the properties of diffusion-weighted imaging for oncological disease sta...
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Fibrolamellar hepatocellular carcinoma

Fibrolamellar hepatocellular carcinoma is a distinct histological variant of hepatocellular carcinoma characterized on microscopy by laminated fibrous layers between the tumor cells. It is important as it has different demographics and risk factors compared to "standard" hepatocellular carcinoma...
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PET-CT indications

PET-CT is a combination of cross-sectional anatomic information provided by CT and the metabolic information provided by positron emission tomography (PET). PET is most commonly performed with 2-[F-18]fluoro-2-deoxy-D-glucose (FDG). Fluorine-18 (F-18) is an unstable radioisotope and has a half-...
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Mandibular lesions

Mandibular lesions are myriad and common. The presence of teeth results in lesions that are specific to the mandible (and maxilla) and a useful classification that defines them as odontogenic or non-odontogenic. While it may often not be possible to make a diagnosis on imaging alone, this classi...
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Labeled imaging anatomy cases

This article lists a series of labeled imaging anatomy cases by body region and modality. Brain CT head: non-contrast axial CT head: non-contrast coronal CT head: non-contrast sagittal CT head: non-contrast axial with clinical questions CT head: angiogram axial CT head: angiogram coronal ...
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International Society of Urological Pathology Vancouver classification of renal neoplasia (historical)

The International Society of Urological Pathology Vancouver classification of renal neoplasia is a now-outdated classification of renal tumors published in 2013. It formed the basis for the WHO classification of tumors of the kidney published in 2016. For reference, the ISUP Vancouver classifica...
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Merkel cell carcinoma

Merkel cell carcinoma is an uncommon neuroendocrine tumor of the dermis which is characterized by aggressive regional nodal invasion, distant metastases, and a high rate of recurrence. Merkel cell carcinoma arises from Merkel cells, which are mechanoreceptor cells present in the skin. Epidemiol...
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Biphenotypic sinonasal sarcoma

Biphenotypic sinonasal sarcoma, initially named low-grade sinonasal sarcoma with neural and myogenic features, is a rare low-grade sarcoma of the nasal and paranasal sinuses. The tumor exhibits both neural and myogenic differentiation and thus can be problematic to diagnose histologically as ele...
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Radiogenomics

Radiogenomics denotes the relationship between the imaging features of a particular disease and various genetic or molecular features. The former is referred to as an imaging phenotype, whereas the later as genomic phenotype.  Radiogenomics, therefore, provides a tool for clinicians to correlat...
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Meningioma

Meningiomas are extra-axial tumors and represent the most common tumor of the meninges. They are a non-glial neoplasm that originates from the meningocytes or arachnoid cap cells of the meninges and are located anywhere that meninges are found, and in some places where only rest cells are presum...
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Spinal ependymoma

Spinal ependymomas are the most common spinal cord tumor overall, seen both in adult and pediatric populations.  This article specifically relates to spinal cord ependymomas. For a discussion of posterior fossa ependymomas and for a general discussion of the pathology refer to the main article:...
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Waldenström macroglobulinemia

Waldenström macroglobulinemia is a subtype of lymphoplasmacytic lymphoma (LPL), a form of B-cell lymphoma. Terminology Waldenström macroglobulinemia is classified as a subtype of lymphoplasmacytic lymphoma with any level of an IgM paraprotein; these two conditions are not synonymous 10. Epide...
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Spermatic cord liposarcoma

Spermatic cord liposarcomas are the most common malignant tumor of the spermatic cord. Most present as painless, slow-growing masses and can be mistaken for inguinal hernias. They are usually well-differentiated and spread by local extension.  Epidemiology In a large population-based registry,...
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Metastatic glioblastoma

Metastatic glioblastoma is a rare progression of glioblastoma, with an incidence of 0.4-0.5% of all glioblastoma cases. The locations can be extraneural, such as leptomeninges and dural venous sinuses, or both extraneural and extracranial, such as solid organs and lymph nodes. Epidemiology In ...
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Ductal carcinoma in situ

Ductal carcinoma in situ (DCIS) refers to a breast carcinoma limited to the ducts with no extension beyond the basement membrane, as a result of which the disease has not infiltrated the parenchyma of the breast and the lymphatics and cannot therefore metastasize. Epidemiology The detection of...
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Bing-Neel syndrome

Bing-Neel syndrome is an extremely rare neurological complication of Waldenström macroglobulinemia where there is malignant lymphocyte infiltration into the central nervous system (CNS). Epidemiology The exact incidence is unknown, however, in one study of patients with Waldenström macroglobul...
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MRI targeted prostate biopsy

MRI targeted prostate biopsy refers to an imaging targeted technique rather than the traditional systematic approach of a prostate biopsy after respective imaging with multiparametric MRI (mpMRI) of the prostate. As a consequence of advances with multiparametric MRI (mpMRI) of the prostate in t...
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Myeloid sarcoma

Myeloid sarcomas, also called granulocytic sarcomas, chloromas, or extramedullary myeloid tumors, are rare extramedullary masses comprised of myeloid precursor cells. These tumors represent a unique presentation of acute myeloid leukemia (AML), whether in isolation to, preceding, or simultaneous...
Article

Osteolytic bone lesion

Osteolytic lesions, lytic or lucent bone lesions are descriptive terms for lesions that replace normal bone or with a vast proportion showing a lower density or attenuation than the normal cancellous bone. This comprises lesions with fatty liquid and solid soft tissue components. Pathology Luc...
Article

Autoimmune encephalitis

Autoimmune encephalitis, also known as autoimmune limbic encephalitis, is an antibody-mediated brain inflammatory process, typically involving the limbic system, although any part of the brain, and central nervous system more broadly, can be involved. Autoimmune encephalitis can be divided broa...

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