Articles

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742 results found
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Spinal dysraphism

Spinal dysraphisms refer to a broad group of malformations affecting the spine and/or surrounding structures in the dorsum of the embryo. They are a form of neural tube defect. Pathology The neural tube is formed by the lengthwise closure of the neural plate, in the dorsum of the embryo. The ...
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Sacral insufficiency fracture

Sacral insufficiency fractures are a subtype of stress fractures, which are the result of normal stresses on abnormal bone, most frequently seen in the setting of osteoporosis. They fall under the broader group of pelvic insufficiency fractures. Epidemiology Risk factors Risk factors are thos...
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Autonomic dysreflexia

Autonomic dysreflexia (AD) is a life-threatening condition prevalent amongst patients with high spinal cord injury (SCI) and may occur any time after injury. It is a syndrome characterized by an exaggerated reflex increase in blood pressure, usually accompanied by bradycardia in response to a st...
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Bagel sign (Behçet disease)

The bagel sign is a radiological sign appreciated on MRI spine that is described in patients with neuro-Behçet disease-associated myelitis. The sign describes the involvement of the spinal cord as seen on axial T2 sequences in patients with myelitis, whereby there is a round hyperintense lesion...
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Trident sign (neurosarcoidosis)

The trident sign is a radiological (MRI) sign described in spinal cord neurosarcoidosis. The sign is formed by the axial appearance of a longitudinally extensive transverse myelitis due to spinal cord neurosarcoidosis, whereby on a T1 post-contrast (gadolinium) MRI sequence, there is central ca...
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Vertebral artery

The vertebral arteries (VA) are paired arteries, each arising from the respective subclavian artery and ascending in the neck to supply the posterior fossa and occipital lobes, as well as provide segmental vertebral and spinal column blood supply. Summary origin: branches of the 1st part of th...
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Fat suppressed imaging

Fat suppression is commonly used in magnetic resonance imaging (MRI) imaging to suppress the signal from adipose tissue or detect adipose tissue 1. It can be applied to both T1 and T2 weighted sequences.  Due to short relaxation times, fat has a high signal on MRI. This high, easily recognized ...
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Odontoid fracture

Odontoid process fracture, also known as a peg or dens fracture, occurs where there is a fracture through the odontoid process of C2. Pathology The mechanism of injury is variable, and can occur both during flexion or extension, and with or without compression 5. Classification There are two...
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Post-dural puncture headache

Post-dural puncture headache, previously known as post-lumbar puncture headache 4, is a common complication after lumbar puncture (LP), which is often performed for cerebrospinal fluid (CSF) sampling, spinal anesthesia, myelography, etc. Epidemiology Post-dural puncture headaches occur after ~...
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Spinal hydatid disease

Spinal hydatid disease is an uncommon manifestation of hydatid disease, caused by the larval stage of Echinococcus granulosus, or less commonly E. alveolaris or E. multilocularis, and describes a spectrum of disease involving the spinal cord, the spine, or both. For a general discussion, and fo...
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Spinal cord compression

Spinal cord compression (SCC) is a surgical emergency, usually requiring prompt surgical decompression to prevent permanent neurological impairment. If the spinal roots below the conus medullaris are involved, and there are characteristic symptoms and signs, it is termed cauda equina syndrome. ...
Article

Nerve root enhancement

Nerve root enhancement is a phenomenon described on post-contrast MRI scans that can be observed in a number of situations. Common causes post-operative nerve root enhancement 6 arachnoiditis leptomeningeal metastases disseminated spinal leptomeningeal metastases neurolymphomatosis HIV va...
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Dural ectasia

Dural ectasia refers to ballooning or widening of the dural sac which can result in posterior vertebral scalloping and is associated with herniation of nerve root sleeves. Clinical presentation Patients with dural ectasia may present with low back pain or radicular pain in the buttocks or legs...
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Arachnoiditis

Arachnoiditis is a broad term encompassing inflammation of the meninges and subarachnoid space. Terminology Arachnoiditis affecting the cauda equina may be referred to as spinal/lumbar adhesive arachnoiditis.  Clinical presentation Lumbar spine arachnoiditis can result in leg pain, sensory c...
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Spinal metastasis

Spinal metastasis is a vague term that can be variably taken to refer to metastatic disease to any of the following: vertebral metastases (94%) may have epidural extension intradural extramedullary metastases (5%) intramedullary metastases (1%) Each of these are discussed separately. Below ...
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Benign notochordal cell tumor

Benign notochordal cell tumors are vertebral lesions that are usually asymptomatic and discovered incidentally on imaging of the head or spine. As this is a poorly-recognized entity, it can often be confused with aggressive vertebral lesions, such as a chordoma, when it is seen on imaging. Term...
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Neurofibromatosis type 2

Neurofibromatosis type 2 (NF2) is a rare autosomal dominant neurocutaneous disorder (phakomatosis) manifesting as a development of multiple CNS tumors. Unlike neurofibromatosis type 1 (NF1), it is not associated with neurofibromas. Instead, patients with this disease have intracranial schwannom...
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Neurosarcoidosis

Central nervous system involvement by sarcoidosis, also termed neurosarcoidosis, is relatively common among patients with systemic sarcoidosis and has a bewildering variety of manifestations, often making diagnosis difficult.  For a general discussion of the underlying condition, please refer t...
Article

Autoimmune glial fibrillary acid protein (GFAP) astrocytopathy

Autoimmune glial fibrillary acid protein (GFAP) astrocytopathy, or simply GFAP astrocytopathy, is a rare inflammatory central nervous system (CNS) disorder. Epidemiology Given the rarity of the condition, epidemiological data pertaining to autoimmune GFAP astrocytopathy are not well establishe...
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Spinal meningioma

Meningiomas arising from the coverings of the spinal cord are one of the two most common intradural extramedullary spinal tumors, representing 25-30% of all such tumors 2.  This article specifically relates to spinal meningiomas. For a discussion on intracranial meningiomas and a general discus...

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