This illustration depicts and contrasts the radiographic features of two common causes of cerebral small vessel disease.
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cerebral amyloid angiopathy (left of diagram)
cortical microbleeds
cortical superficial siderosis
convexity (convexal) subarachnoid haemorrhage (cSAH)
enlarged perivascular spaces of the centrum semiovale
white matter hyperintensities (WMH): subcortical, multiple spot pattern, occipital predominance
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sporadic non-amyloid small vessel disease ("hypertensive arteriopathy") (right of diagram)
deep and subcortical microbleeds
enlarged perivascular spaces of the basal ganglia
deep lacunes
white matter hyperintensities (WMH): deep, more likely to be confluent, periventricular and peri-basal ganglia predominance