Histologically, what is the hallmark of Hodgkin's lymphoma which is not seen in non-Hodgkin's lymphoma?
Hodgkin's lymphoma is characterised by the presence of Reed-Sternberg cells (considered to be a type of B cell).
Large irregular mass in the left upper quadrant measures approx 15 cm in maximal diameter. There is encasement of the GOJ and fundus of the stomach.
Invasion of the spleen with encasement of the splenic hilum. The mass is also inseparable from adjacent diaphragm, with areas of possible invasion (particularly at the dome of the diaphragm). Speckled calcifications are present in the lesion.
Widespread lymphadenopathy. Enlarged lymph nodes are demonstrated around the upper abdominal aorta, coeliac axis and at the porta hepatis.There is extension into the liver around hepatic arteries.
Abnormal appearance of the pancreatic head, neck and tail which is invaded by tumour.
Multiple cysts in both kidneys, measuring up to 9.5 cm at the lower poles.