Procedure: Laparoscopic right partial nephrectomy. Diagnosis: Histologic type: Clear cell renal cell carcinoma. Histologic grade (Fuhrman nuclear grade): Grade 2. Tumor size: 2.5 x 1.5 x 1.0 cm. Tumor focality: Unifocal. Macroscopic extent of tumor: Tumor limited to kidney. Microscopic tumor extension: Tumor limited to kidney. Margins: Involved by invasive carcinoma: Renal parenchymal margins (partial nephrectomy only). Sarcomatoid features, tumor necrosis and lymphovascular invasion: Not identified. Pathologic staging: pT1a pNx pMx. Immunohistochemical stains showed that the carcinoma cells are immunoreactive to vimentin, CD10 and E-Cadherin. There is no immunoreactivity to CD117 (C-Kit) and cytokeratin 7. Colloidal iron special stain was essentially negative. This immunohistochemical pattern confirms the diagnosis of conventional type, renal cell carcinoma, clear cell type.
Procedure: Left partial nephrectomy. Diagnosis: Histologic type: Clear cell renal cell carcinoma. Grade: Grade 2. Tumor size: 3.5 x 3.5 x 3.5 cm. Tumor focality: Unifocal. Anatomic extent of tumor: Tumor extension into perinephric tissue (beyond renal capsule). Margins: Uninvolved by invasive carcinoma. Sarcomatoid features: 5%. Tumor necrosis: 15%. Lymphovascular invasion: Not identified. Regional lymph nodes (two): Negative for malignancy. Pathologic staging: pT3a pN0 pMx.