Bilateral perisylvian polymicrogyria

Case contributed by Ala' Y Ibrahim
Diagnosis certain

Presentation

Developmental delay

Patient Data

Age: 22 months
Gender: Female

Excessively small & disorganized gyral convolutions with shallow sulci, creating the appearance of diffuse nodularity along the surface of the cortex & at the GM-WM junction of frontal, parietal and temporal lobes along Sylvian fissure bilaterally in keeping with bilateral perisylvian polymicrogyria. The Sylvian fissures show continuation into the superior parietal lobule.

Case Discussion

Polymicrogyria is considered malformation of late neuronal migration and cortical organization.

Underlying etiology includes intrauterine infection (CMV), ischemia or gene mutation.

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