Presentation
Developmental delay
Patient Data
Age: 22 months
Gender: Female
From the case:
Bilateral perisylvian polymicrogyria
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Excessively small & disorganized gyral convolutions with shallow sulci, creating the appearance of diffuse nodularity along the surface of the cortex & at the GM-WM junction of frontal, parietal and temporal lobes along Sylvian fissure bilaterally in keeping with bilateral perisylvian polymicrogyria. The Sylvian fissures show continuation into the superior parietal lobule.
Case Discussion
Polymicrogyria is considered malformation of late neuronal migration and cortical organization.
Underlying etiology includes intrauterine infection (CMV), ischemia or gene mutation.