Presentation
History of epilepsy. Fever with altered state of consciousness (Galsgow score at 13/15). MRI to rule out encephalitis.
Patient Data
Age: 7 years
Gender: Female
From the case:
Cytotoxic lesion of the corpus callosum (CLOCC)
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Midline ovoid region of abnormal restricted diffusion with T2/FLAIR hyperintensity in the splenium of the corpus callosum. This lesion demonstrates a reduced T1 signal and there is no enhancement.
No intracranial bleeding. No midline shift.
The brain and cerebellar parenchyma are unremarkable.
Case Discussion
The most likely cause of this CLOCC is antiseizure medication since there are no signs of CNS infection and the lumbar puncture was unremarkable. Besides, the blood tests were normal and the patient did not report any drug intake other than her usual antiseizure medications
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