Cytotoxic lesions of the corpus callosum

Case contributed by Dijendra Nath Biswas
Diagnosis almost certain

Presentation

Postpartum psychosis and electrolyte imbalance.

Patient Data

Age: 20 years
Gender: Female

T2W/FLAIR hyperintensity, T1W isointense lesion is seen in the splenium of the corpus callosum with significant diffusion restriction.

No others lesions are seen in the brain parenchyma.

Case Discussion

This patient had a blood sodium level of 152 mEq/L and a potassium level of 5.6 mEq/L. In this clinical context, the features are almost certainly those of cytotoxic lesions of the corpus callosum (CLOCCs).

Followup clinical information or imaging are unfortunately not available.

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