Cytotoxic lesions of the corpus callosum (CLOCCs)

Case contributed by Keshaw Kumar
Diagnosis almost certain

Presentation

Acute gastroenteritis with hyponatremia and weakness.

Patient Data

Age: 10 years
Gender: Male

There is a small area of signal alteration in the splenium of the corpus callosum which appears hypointense on T1W images, hyperintense on T2W/FLAIR images with true diffusion restriction on DWI, and no significant enhancement on T1W post-contrast images.

Case Discussion

Imaging findings are suggestive of cytotoxic lesions of the corpus callosum (CLOCCs), secondary to hyponatremia.

Co-author: Dr Vivek Ranjan (Pediatrician).

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