Fibro-osseous mandibular lesion

Case contributed by Rodney Strahan
Diagnosis certain

Presentation

A long history of left facial swelling. Painless enlarging mass in the left jaw.

Patient Data

Age: 20 years
Gender: Female
x-ray

Large expansile lytic lesion replacing the left mandible. There is thin rim calcification with a bubbly appearance. An unerupted molar tooth is present within the posterior peripheral part of the mass.

Following surgical removal, the pathology report on the specimen was:

Microscopic: Sections show a hard and soft tissue specimen consisting of trabeculae of vital bone and droplets of cementum-like material seen in association with a variable cellular fibrous connective tissue stoma.

Comment: The histopathological findings, in conjunction with the clinical and radiographic presentation, are most compatible with cemento-osseous dysplasia variant expansive osseous dysplasia or gigantiform cementoma.

Final Diagnosis: Benign fibro-osseous lesion

Case Discussion

The patient presented late with a long history of left facial swelling. Cross-sectional imaging was not available.

The differential of the expansile lytic lesion would include the benign mandibular lesions as there are no aggressive features seen on plain radiographs; ameloblastoma, or fibro-osseous lesion, depending on where the lesion originated. The originating tissues cannot be ascertained from plain radiographs.

Following surgical removal, the pathology report gave a final diagnosis of a benign fibro-osseous lesion.

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