Frontotemporal lobar degeneration

Case contributed by Qutaiba Jaf'ar Mahmoud
Diagnosis probable

Presentation

History of progressive memory loss and deterioration in language function.

Patient Data

Age: 70 years
Gender: Male

Asymmetrical atrophy of the left temporal lobe and hippocampus, giving a 'knife blade' sign, with hyper signal intensity on FLAIR images, probably due to gliosis, without significant frontal lobe atrophy, associated with dilatation of the temporal horn of the left lateral ventricle.

Unremarkable right temporal lobe.

No diffusion restriction.

Case Discussion

The above-mentioned radiological findings and clinical manifestations suggest frontotemporal dementia (FTD).

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