Granulomatosis with polyangiitis

Case contributed by Mark Wanderley
Diagnosis almost certain

Presentation

The patient presents to the emergency department with anasarca and dyspnea. Upon investigation, he is found to have proteinuria and hematuria, as well as deep vein thrombosis of the lower limbs.

Patient Data

Age: 65 years
Gender: Male

Bilateral ground glass and confluent irregular consolidation, with central and upper lobe predominance. There are some irregular cavitated lung nodules with thick walls.

Bilateral pleural effusions and ascites.

Case Discussion

The patient had very elevated C-ANCA levels, confirming the hypothesis of granulomatosis with polyangiitis. The lung findings of alveolar hemorrhage and cavitated nodules are typical. Pleural effusion and ascites are compatible with systemic congestion, secondary to nephrotic syndrome.

How to use cases

You can use Radiopaedia cases in a variety of ways to help you learn and teach.

Creating your own cases is easy.

Updating… Please wait.

 Unable to process the form. Check for errors and try again.

 Thank you for updating your details.