Hepatocellular carcinoma (HCC)

Case contributed by Ammar Haouimi
Diagnosis almost certain

Presentation

Known patient for chronic hepatitis B with a history of splenectomy following RTA 35 years ago. Presented with elevated alpha-fetoprotein.

Patient Data

Age: 80 years
Gender: Female

Dysmorphic liver with hypertrophy of the lateral segments of the left lobe (segments 2 and 3) and caudate lobe with concomitant atrophy of the posterior segments (5 and 6) of the right lobe.

Well-defined hypodense ovoid mass of the right lobe of the liver centered on the segments (5, 6, 8).

The postcontrast demonstrates a vivid enhancement on the arterial phase, washout on the portal phase, and peripheral rim enhancement on the delayed phase (capsule).

Calcified hydatid cyst of the segment 8 (known).

Spleen not seen (history of splenectomy).

Simple left renal cysts.

Degenerative spine with osteoporotic compression fractures.

Case Discussion

The CT features are most consistent with hepatocellular carcinoma (HCC) in a patient known for chronic hepatitis B with elevated alpha-fetoprotein.

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