Lady Windermere syndrome

Case contributed by Andrea Horváth Trajtler
Diagnosis almost certain

Presentation

Recurrent right middle lobe pneumonia. Chronic centrilobular nodularity.

Patient Data

Age: 80 years
Gender: Female
ct

Extensive bronchiectasis and volume loss predominantly affecting the right middle lobe and the lingula segment of the left upper lobe. Bronchiectasis is also present at the lung bases.

Centrilobular nodules and tree-in-bud nodularity are seen with basal predominance.

Case Discussion

Sputum was positive for Mycobacterium avium 5 years ago and the patient underwent antituberculosis treatment.

This pattern of lung involvement (right middle lobe and lingula predominant) with bronchiectasis and volume loss is typical for Mycobacterium avium complex (MAC) infection.

This patient also had a right mastectomy for breast cancer and follow-up CT scans had been performed to rule out metastasis.

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