Multiple system atrophy - cerebellar subtype (MSA-C)

Case contributed by Zentout Sofiane
Diagnosis almost certain

Presentation

Ataxia.

Patient Data

Age: 65 years
Gender: Male

MRI demonstrates atrophy of the brainstem, cerebellum, and symmetric atrophy of middle cerebellar peduncles.

There are also cruciform hyperintensities in the pons "Hot cross bun sign".

White matter hyperintensities in both cerebral hemispheres suggest chronic vessel ischemia.

Case Discussion

MRI features are consistent with multiple system atrophy - cerebellar subtype (MSA-C) that demonstrated the hot cross bun sign.

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